Edex

Adult Dosing .

Dosage forms:  INJ (pre-filled syringe): 10 mcg per mL, 20 mcg per mL, 40 mcg per mL

erectile dysfxn

[vasculogenic, psychogenic, or mixed etiology]

Dose: individualize dose intracavernously up to 3x/wk prn; Start: 2.5 mcg intracavernously x1, then w/in 1h may give 5 mcg intracavernously x1 if partial response or give 7.5 mcg intracavernously x1 if no response, then if additional titration needed, may incr. dose by 5-10 mcg/dose given at least 24h apart until optimal response achieved; Max: 2 doses/24h during initial titration, then 1 dose/24h; 40 mcg/dose; Info: duration of erection not to exceed 1h; use lowest effective dose

[pure neurogenic etiology]

Dose: individualize dose intracavernously up to 3x/wk prn; Start: 1.25 mcg intracavernously x1, then w/in 1h may give 2.5 mcg intracavernously x1 if no response or give 2.5 mcg intracavernously x1 24h later if partial response, then if additional titration needed, may incr. dose to 5 mcg intracavernously x1 24h later, then may incr. dose by 5 mcg/dose given at least 24h apart until optimal response achieved; Max: 2 doses/24h during initial titration, then 1 dose/24h; 40 mcg/dose; Info: duration of erection not to exceed 1h; use lowest effective dose

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[not defined]

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.