sevelamer hydrochloride

Adult Dosing .

Dosage forms:  TAB: 400 mg, 800 mg

hyperphosphatemia, dialysis pts

[individualize dose PO tid]

Start: 800 mg PO tid if PO4 5.6-7.4 mg/dL, 1200-1600 mg PO tid if PO4 7.5-8.9 mg/dL, or 1600 mg PO tid if PO4 >9 mg/dL; Max: 13 g/day; Info: may titrate by 400-800 mg/dose q2wk to target serum PO4 levels; give w/ meals

renal dosing

[see below]

renal impairment: not defined

HD/PD: no adjustment; no supplement

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  TAB: 400 mg, 800 mg

hyperphosphatemia, dialysis pts (off-label)

[children or adolescents]

Dose: individualize dose PO tid; Start: 400-800 mg PO tid; Info: may titrate by 400 mg/dose q2-4wk to target serum PO4 levels; give w/ meals

renal dosing

[see below]

renal impairment: not defined

HD/PD: no adjustment; no supplement

hepatic dosing

[not defined]