sevoflurane inhaled

Adult Dosing .

Dosage forms:  VOLATILE LIQUID

general anesthesia induction

[dosing varies]

Info: titrate inhalation to effect; MAC in 40 yo = 2.1% in 100% oxygen = 1.1% in 65% nitrous oxide; blood/gas partition coefficient (37C) = 0.63-0.69

general anesthesia maintenance

[dosing varies]

Info: titrate inhalation to effect; typical range 0.5-3%; MAC in 40 yo = 2.1% in 100% oxygen = 1.1% in 65% nitrous oxide; blood/gas partition coefficient (37C) = 0.63-0.69

renal dosing

[see below]

renal impairment: not defined; Info: caution advised if Cr >1.5

HD/PD: not defined

hepatic dosing

[see below]

mild-moderate impairment: no adjustment; severe impairment: not defined

Peds Dosing .

Dosage forms:  VOLATILE LIQUID

general anesthesia induction

[dosing varies by age]

Info: titrate inhalation to effect; suitable for mask induction; MAC in 100% oxygen in 0-1 mo = 3.2%, in 1-6 mo = 3%, in 6 mo to 3 yo = 2.8%, in 3-12 yo = 2.5%

general anesthesia maintenance

[dosing varies by age]

Info: titrate inhalation to effect; MAC in 100% oxygen in 0-1 mo = 3.5%, in 1-6 mo = 3%, in 6 mo to 3 yo = 2.8%, in 3-12 yo = 2.5%

renal dosing

[see below]

renal impairment: not defined; Info: caution advised if Cr >1.5

HD/PD: not defined

hepatic dosing

[see below]

mild-moderate impairment: no adjustment; severe impairment: not defined