Folotyn

Adult Dosing .

Dosage forms:  INJ

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses, premeds, concomitant meds to mitigate toxicity, and dosing including toxicity-related dose adjustments

peripheral T-cell lymphoma, relapsed or refractory

[30 mg/m^2/dose IV x1 on days 1, 8, 15, 22, 29, 36 of 49-day cycle]

Info: initiate vitamin supplementation with IM vitamin B12 within 10wk before 1st dose, continue during tx; initiate PO folic acid 10 days before 1st dose, continue during tx and x30 days after last dose

renal dosing

[see below]

eGFR 15-29: 15 mg/m^2/dose x1 on days 1, 8, 15, 22, 29, 36 of 49-day cycle; eGFR <15: avoid use

HD/PD: avoid use

hepatic dosing

[not defined]

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.