Halaven

Adult Dosing .

Dosage forms:  INJ

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

breast CA, metastatic

[1.4 mg/m^2/dose IV x1 on days 1, 8 of 21-day cycle]

Info: for pts who have received at least 2 prior tx, incl. an anthracycline and a taxane

liposarcoma, unresectable or metastatic

[1.4 mg/m^2/dose IV x1 on days 1, 8 of 21-day cycle]

Info: for pts who have received an anthracycline-containing regimen

renal dosing

[see below]

CrCl 15-49: give 1.1 mg/m^2/dose x1 on days 1, 8 of 21-day cycle; CrCl <15: not defined

HD/PD: not defined

hepatic dosing

[adjust dose amount]

Child-Pugh Class A: give 1.1 mg/m^2/dose x1 on days 1, 8 of 21-day cycle; Child-Pugh Class B: give 0.7 mg/m^2/dose x1 on days 1, 8 of 21-day cycle; Child-Pugh Class C: not defined

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.