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raxibacumab
generic
Black Box Warnings .
Appropriate Use
must admin. in monitored setting w/ appropriate equipment, medication, and trained personnel to manage hypersensitivity, anaphylaxis, and shock
Hypersensitivity and Anaphylaxis
may occur during tx; monitor pts for hypersensitivity rxn s/sx during infusion and for a period of time after admin; D/C infusion immed. and treat appropriately if hypersensitivity rxn or anaphylaxis occurs
Adult Dosing .
Dosage forms: INJ
Restricted Distribution in US
- [distributed directly to CDC]
inhalational anthrax tx
- [40 mg/kg/dose IV x1]
- Info: premed w/ antihistamine
inhalational anthrax prophylaxis, post-exposure
- [40 mg/kg/dose IV x1]
- Info: not 1st-line agent; premed w/ antihistamine
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: INJ
Restricted Distribution in US
- [distributed directly to CDC]
inhalational anthrax tx
- [<10 kg]
- Dose: 80 mg/kg/dose IV x1; Info: premed w/ antihistamine
- [10-40 kg]
- Dose: 60 mg/kg/dose IV x1; Info: premed w/ antihistamine
- [>40 kg]
- Dose: 40 mg/kg/dose IV x1; Info: premed w/ antihistamine
inhalational anthrax prophylaxis, post-exposure
- [<10 kg]
- Dose: 80 mg/kg/dose IV x1; Info: not 1st-line agent; premed w/ antihistamine
- [10-40 kg]
- Dose: 60 mg/kg/dose IV x1; Info: not 1st-line agent; premed w/ antihistamine
- [>40 kg]
- Dose: 40 mg/kg/dose IV x1; Info: not 1st-line agent; premed w/ antihistamine
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]