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Adasuve
loxapine inhaled
Black Box Warnings .
Appropriate Use
restricted distribution program (Adasuve REMS) due to bronchospasm risk; admin. only at enrolled healthcare facility w/ adequate ability to manage acute bronchospasm and ready access to emergency response services; facilities must have short-acting bronchodilator (e.g., albuterol) incl. nebulizer and inhalation solution for immediate bronchospasm tx; screen pts for hx or sx of asthma, COPD or other lung dz, and conduct physical exam for respiratory dz signs
Bronchospasm
may occur and could lead to respiratory distress and respiratory arrest; monitor for bronchospasm s/sx
Dementia-Related Psychosis
not approved for dementia-related psychosis; incr. mortality risk in elderly pts on antipsychotic tx for dementia-related psychosis
Adult Dosing .
Dosage forms: DPI: 10 mg per blister
Restricted Distribution in US
- [1-855-755-0492 or www.adasuverems.com for more info]
agitation, schizophrenia or bipolar I disorder-assoc.
- [1 puff inhaled q24h prn]
renal dosing
- [see below]
- renal impairment: no adjustment
- HD/PD: not defined
hepatic dosing
- [no adjustment]
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.