Hetlioz

Adult Dosing .

Dosage forms:  CAP: 20 mg

Restricted Distribution in US

[1-844-438-5469 or www.hetlioz.com for more info]

Special Note

[formulation clarification]

Info: tasimelteon capsule not interchangeable w/ oral suspension

non-24h sleep-wake disorder

[20 mg PO qhs]

Info: give w/o food 1h before bedtime

sleep disturbance, Smith-Magenis syndrome

[20 mg PO qhs]

Info: give w/o food 1h before bedtime

renal dosing

[see below]

renal impairment: no adjustment

HD: no adjustment; no supplement; PD: not defined

hepatic dosing

[see below]

Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined

Peds Dosing .

Dosage forms:  CAP: 20 mg

Restricted Distribution in US

[1-844-438-5469 or www.hetlioz.com for more info]

Special Note

[formulation clarification]

Info: tasimelteon capsule not interchangeable w/ oral suspension

sleep disturbance, Smith-Magenis syndrome

[16 yo and older]

Dose: 20 mg PO qhs; Info: give w/o food 1h before bedtime

renal dosing

[see below]

renal impairment: no adjustment

HD: no adjustment; no supplement; PD: not defined

hepatic dosing

[see below]

Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined