Beleodaq

Adult Dosing .

Dosage forms:  INJ

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing including toxicity-related dose adjustments

peripheral T-cell lymphoma, relapsed or refractory

[1000 mg/m^2/dose IV x1 on days 1-5 of 21-day cycle]

Info: decr. dose to 750 mg/m^2/dose in UGT1A1*28 homozygous allele carriers

renal dosing

[see below]

CrCl 30-59: 500 mg/m^2/dose on days 1-5 of 21-day cycle; CrCl <30: avoid use

HD/PD: not defined

hepatic dosing

[see below]

bilirubin 1.6-3x ULN: 500 mg/m^2/dose on days 1-5 of 21-day cycle; bilirubin >3x ULN: avoid use

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.