Plegridy

Adult Dosing .

Dosage forms:  INJ (SC auto-injector): 125 mcg; INJ (SC auto-injector starter pack): 63 mcg x1 and 94 mcg x1; INJ (SC pre-filled syringe): 125 mcg per 0.5 mL; INJ (SC pre-filled syringe starter pack): 63 mcg per 0.5 mL x1 and 94 mcg per 0.5 mL x1; INJ (IM pre-filled syringe): 125 mcg per 0.5 mL

multiple sclerosis, relapsing forms

[SC route]

Dose: 125 mcg SC q14 days; Start: 63 mcg SC x1 on day 1, then 94 mcg SC x1 on day 15, then 125 mcg SC x1 on day 29, then 125 mcg SC q14 days; Info: for patients with clinically isolated syndrome, relapsing-remitting disease, or active secondary progressive disease

[IM route]

Dose: 125 mcg IM q14 days; Start: 63 mcg IM x1 on day 1, then 94 mcg IM x1 on day 15, then 125 mcg IM x1 on day 29, then 125 mcg IM q14 days; Info: for patients with clinically isolated syndrome, relapsing-remitting disease, or active secondary progressive disease; use pre-filled IM syringe with titration devices to deliver start doses of 63 mcg, 94 mcg

renal dosing

[see below]

mild-moderate impairment: no adjustment; severe impairment: caution advised, monitor for adverse effects

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.