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Aptensio XR
methylphenidate
Black Box Warnings .
Abuse, Misuse, and Addiction
CNS stimulants have high potential for abuse and misuse, can lead to substance use disorder, incl. addiction; misuse and abuse can result in overdose and death, risk incr. w/ higher doses or unapproved admin. methods; assess risk for abuse, misuse, and addiction before prescribing and throughout tx; educate pts and families about risks and proper drug storage and disposal; monitor frequently for s/sx of abuse, misuse, and addiction during tx
Adult Dosing .
Dosage forms: ER CAP (40% IR/60% ER): 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg
Special Note
- [strength clarification]
- Info: all strengths expressed as methylphenidate hydrochloride
- [formulation clarification]
- Info: methylphenidate ER products not interchangeable; do not substitute on a mg to mg basis
ADHD
- [10-60 mg PO qam]
- Start: 10 mg PO qam, may incr. by 10 mg/day q7 days; Max: 60 mg/day; Info: duration 12h; give consistently w/ or w/o food; may open cap, but do not crush/chew contents
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: ER CAP (40% IR/60% ER): 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg
Special Note
- [strength clarification]
- Info: all strengths expressed as methylphenidate hydrochloride
Special Note
- [formulation clarification]
- Info: methylphenidate ER products not interchangeable; do not substitute on a mg to mg basis
ADHD
- [6 yo and older]
- Dose: 10-60 mg PO qam; Start: 10 mg PO qam, may incr. by 10 mg/day q7 days; Max: 60 mg/day; Info: duration 12h; give consistently w/ or w/o food; may open cap, but do not crush/chew contents
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]