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Ninlaro
ixazomib
Adult Dosing .
Dosage forms: CAP: 2.3 mg, 3 mg, 4 mg
Special Note
- [uses, dosing may vary]
- Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing including toxicity-related dose adjustments
multiple myeloma, relapsed or refractory
- [4 mg PO x1 on days 1, 8, 15 of 28-day cycle]
- Info: part of multi-drug chemo regimen; give at least 1h before or 2h after food; do not open cap
renal dosing
- [adjust dose amount]
- CrCl <30: start 3 mg x1 on days 1, 8, 15 of 28-day cycle
- HD: start 3 mg x1 on days 1, 8, 15 of 28-day cycle; no supplement after dialysis; PD: start 3 mg x1 on days 1, 8, 15 of 28-day cycle; no supplement
hepatic dosing
- [adjust dose amount]
- bilirubin >1.5x ULN: start 3 mg x1 on days 1, 8, 15 of 28-day cycle
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.