Mektovi

Adult Dosing .

Dosage forms:  TAB: 15 mg

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

BRAF V600E- or V600K-positive melanoma, unresectable or metastatic

[45 mg PO q12h]

Info: use w/ encorafenib

BRAF V600E-positive non-small cell lung CA, metastatic

[45 mg PO q12h]

Info: use w/ encorafenib

renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

hepatic dosing

[adjust dose amount]

bilirubin >1.5x ULN: 30 mg q12h

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.