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Recarbrio
imipenem/ cilastatin/ relebactam
Adult Dosing .
Dosage forms: INJ
Special Note
- [strength clarification]
- Info: doses expressed as total imipenem + cilastatin + relebactam amt; 1.25 g imipenem/cilastatin/relebactam contains 0.5 g imipenem + 0.5 g cilastatin + 0.25 g relebactam
pneumonia, hospital-acquired or ventilator-assoc.
- [1.25 g IV q6h x7 days]
- Info: may extend duration based on clinical response; refer to IDSA guidelines
intra-abdominal infections, complicated
- [1.25 g IV q6h x4-14 days]
- Info: for pts w/ limited or no alternative tx options; duration varies w/ infection type, pathogen susceptibility
UTI, complicated
- [1.25 g IV q6h x4-14 days]
- Info: for pts w/ limited or no alternative tx options; duration varies w/ infection type, pathogen susceptibility
renal dosing
- [see below]
- CrCl 60-89: 1 g q6h; CrCl 30-59: 0.75 g q6h; CrCl 15-29: 0.5 g q6h; CrCl <15: avoid unless HD w/in 48h
- HD: 0.5 g q6h, on dialysis days admin. after dialysis; consider supplement if next maint. dose not due right after dialysis; PD: not defined
hepatic dosing
- [no adjustment]
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.