Tazverik

Adult Dosing .

Dosage forms:  TAB: 200 mg

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

epithelioid sarcoma, locally advanced or metastatic

[800 mg PO bid]

Info: for patients ineligible for complete resection; do not cut/crush/chew tab

follicular lymphoma, relapsed or refractory

[800 mg PO bid]

Info: for patients w/ EZH2 mutation who have received at least 2 prior tx or patients w/ no alternative tx options; do not cut/crush/chew tab

renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

hepatic dosing

[see below]

bilirubin 1.1-1.5x ULN or AST >ULN: no adjustment; bilirubin >1.5x ULN: not defined

Peds Dosing .

Dosage forms:  TAB: 200 mg

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

epithelioid sarcoma, locally advanced or metastatic

[16 yo and older]

Dose: 800 mg PO bid; Info: for patients ineligible for complete resection

renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

hepatic dosing

[see below]

bilirubin 1.1-1.5x ULN or AST >ULN: no adjustment; bilirubin >1.5x ULN: not defined