Tepmetko

Adult Dosing .

Dosage forms:  TAB: 225 mg

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing including toxicity-related dose adjustments

MET-positive non-small cell lung CA, metastatic

[450 mg PO qd]

Info: for tumors with mesenchymal-epithelial transition (MET) exon 14 skipping; give with food; do not cut/crush/chew, but may disperse tab in water

renal dosing

[see below]

CrCl >30: no adjustment; CrCl <30: not defined

hepatic dosing

[see below]

Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.