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menthae piperitae folium
peppermint (Mentha x piperita)
Entire Monograph
Reported Uses
- NOTE: see Herb & Supplement Effectiveness Rating Definitions table
- abdominal pain [Insufficient Evidence]
- anxiety [Insufficient Evidence]
- athletic performance [Insufficient Evidence]
- barium enema-related colonic spasm [Possibly Effective]
- cognitive function [Insufficient Evidence]
- common cold [Insufficient Evidence]
- dental plaque [Insufficient Evidence]
- dysmenorrhea [Insufficient Evidence]
- dyspepsia [Possibly Effective]
- endoscopy-assoc. adverse effects [Possibly Effective]
- esophageal spasm [Insufficient Evidence]
- fatigue [Insufficient Evidence]
- halitosis [Insufficient Evidence]
- hot flashes, breast CA-assoc. [Insufficient Evidence]
- IBS [Likely Effective]
- insomnia [Insufficient Evidence]
- menopausal sx [Insufficient Evidence]
- migraine, acute [Insufficient Evidence]
- mosquito repellent [Insufficient Evidence]
- myalgia [Insufficient Evidence]
- nausea/vomiting, chemo-related [Possibly Effective]
- nausea/vomiting, postop [Insufficient Evidence]
- nausea/vomiting, pregnancy-related [Insufficient Evidence]
- nipple fissures [Possibly Effective]
- oral mucositis [Insufficient Evidence]
- osteoarthritis [Insufficient Evidence]
- pain [Insufficient Evidence]
- post-herpetic neuralgia [Insufficient Evidence]
- postop ileus [Insufficient Evidence]
- postop pain [Insufficient Evidence]
- postop sleep disturbance [Insufficient Evidence]
- preop anxiety [Insufficient Evidence]
- pressure ulcer [Possibly Effective]
- pruritus [Insufficient Evidence]
- small intestinal bacterial overgrowth (SIBO) [Insufficient Evidence]
- stress [Insufficient Evidence]
- tension headache [Possibly Effective]
- toothache [Insufficient Evidence]
- urticaria [Insufficient Evidence]
Reported Doses
Safety/efficacy may not be established; reported doses may be derived from limited or potentially inadequate studies w/ variable regimens, multi-ingredient products, or where concentration of active ingredients may vary widely
Effectiveness Ratings
- [see Herb & Supplement Effectiveness Rating Definitions table]
anxiety
- [Insufficient Evidence]
- Dose: 3 gtt peppermint oil diffused for inhaled aromatherapy x1h
athletic performance
- [Insufficient Evidence]
- Dose: 0.05 mL peppermint oil/500 mL water PO x1 given 30min before exercise
barium enema-related colonic spasm
- [Possibly Effective]
- Info: peppermint oil added to barium enema preparation
dental plaque
- [Insufficient Evidence]
- Dose: 10 mL (1.6 mg/g mouthwash) swish/spit bid
dysmenorrhea
- [Insufficient Evidence]
- Dose: 561 mg PO qd x3 days; Start: 1st day of menstruation
dyspepsia
- [Possibly Effective]
- Dose: 90 mg PO bid-tid; Alt: 16.7 mg/1 mL PO tid
endoscopy-assoc. adverse effects
- [Possibly Effective]
- Dose: 187 mg ER PO x1 given 4h before procedure
esophageal spasm
- [Insufficient Evidence]
- Dose: 5 gtt peppermint oil/10 mL water PO x1
fatigue
- [Insufficient Evidence]
- Dose: 3 gtt peppermint oil diffused for inhaled aromatherapy x20min qhs
halitosis
- [Insufficient Evidence]
- Dose: apply 0.5% peppermint oil topically bid; Info: used w/ tea tree oil and lemon oil
IBS
- [Likely Effective]
- Dose: 180-450 mg PO bid-qid
insomnia
- [Insufficient Evidence]
- Dose: 3 gtt peppermint oil diffused for inhaled aromatherapy x20min qhs
menopausal sx
- [Insufficient Evidence]
- Dose: apply 2 gtt peppermint oil topically to hand and arm for aromatherapy massage x30min 2x/wk
migraine, acute
- [Insufficient Evidence]
- Dose: apply 1-2 gtt (1.5% peppermint oil) intranasally x1 at start of migraine
nausea/vomiting, chemo-related, adult pts
- [Possibly Effective]
- Dose: 40 gtt peppermint oil/20 mL water PO q8h after chemo; Alt: 2 gtt peppermint oil diffused for inhaled aromatherapy x30min; apply 1 gtt peppermint oil topically below nose tid
nausea/vomiting, chemo-related, peds pts
- [Possibly Effective]
- Dose: 2 gtt peppermint oil/80 mL water diffused for inhaled aromatherapy x30min before chemo, then cont. 2h and 4h after chemo 1x/wk; Info: used w/ lemon oil
nausea/vomiting, postop
- [Insufficient Evidence]
- Dose: 10-30% peppermint oil diffused for inhaled aromatherapy x1; Start: 1-4h after surgery
nausea/vomiting, pregnancy-related
- [Insufficient Evidence]
- Dose: 5% peppermint oil diffused for inhaled aromatherapy q5min prn
nipple fissures
- [Possibly Effective]
- Dose: apply topically after breastfeeding; Info: products incl. gel, solution, cream
postop ileus
- [Insufficient Evidence]
- Dose: 20 gtt peppermint oil PO x1 given 4h after surgery, then 20 gtt peppermint oil PO q1h x3 doses
postop pain
- [Insufficient Evidence]
- Dose: 0.1 mL (10% peppermint oil) diffused for inhaled aromatherapy tid x7 doses; Alt: 5 gtt peppermint oil diffused for inhaled aromatherapy x1 after surgery
postop sleep disturbance
- [Insufficient Evidence]
- Dose: 0.1 mL (10% peppermint oil) diffused for inhaled aromatherapy tid x7 doses
pressure ulcer
- [Possibly Effective]
- Dose: apply 0.2% gel topically tid
pruritus
- [Insufficient Evidence]
- Dose: apply 5% peppermint oil in petrolatum topically bid; Alt: apply 3.6% gel topically x24h covered w/ gauze; apply 0.5% peppermint oil topically bid
stress
- [Insufficient Evidence]
- Dose: 5 gtt peppermint oil diffused for inhaled aromatherapy x1
tension headache
- [Possibly Effective]
- Dose: apply 10% peppermint oil topically x1
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