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menthae piperitae folium

peppermint (Mentha x piperita)

Sections:

  • Entire Monograph
  • Reported Uses
  • Reported Doses
  • Cautions
  • Drug Interactions
  • Adverse Reactions
  • Synonyms
  • Other Info
  • Add to Interaction Check

Entire Monograph

Reported Uses

  • NOTE: see Herb & Supplement Effectiveness Rating Definitions table
  • abdominal pain [Insufficient Evidence]
  • anxiety [Insufficient Evidence]
  • athletic performance [Insufficient Evidence]
  • barium enema-related colonic spasm [Possibly Effective]
  • cognitive function [Insufficient Evidence]
  • common cold [Insufficient Evidence]
  • dental plaque [Insufficient Evidence]
  • dysmenorrhea [Insufficient Evidence]
  • dyspepsia [Possibly Effective]
  • endoscopy-assoc. adverse effects [Possibly Effective]
  • esophageal spasm [Insufficient Evidence]
  • fatigue [Insufficient Evidence]
  • halitosis [Insufficient Evidence]
  • hot flashes, breast CA-assoc. [Insufficient Evidence]
  • IBS [Likely Effective]
  • insomnia [Insufficient Evidence]
  • menopausal sx [Insufficient Evidence]
  • migraine, acute [Insufficient Evidence]
  • mosquito repellent [Insufficient Evidence]
  • myalgia [Insufficient Evidence]
  • nausea/vomiting, chemo-related [Possibly Effective]
  • nausea/vomiting, postop [Insufficient Evidence]
  • nausea/vomiting, pregnancy-related [Insufficient Evidence]
  • nipple fissures [Possibly Effective]
  • oral mucositis [Insufficient Evidence]
  • osteoarthritis [Insufficient Evidence]
  • pain [Insufficient Evidence]
  • post-herpetic neuralgia [Insufficient Evidence]
  • postop ileus [Insufficient Evidence]
  • postop pain [Insufficient Evidence]
  • postop sleep disturbance [Insufficient Evidence]
  • preop anxiety [Insufficient Evidence]
  • pressure ulcer [Possibly Effective]
  • pruritus [Insufficient Evidence]
  • small intestinal bacterial overgrowth (SIBO) [Insufficient Evidence]
  • stress [Insufficient Evidence]
  • tension headache [Possibly Effective]
  • toothache [Insufficient Evidence]
  • urticaria [Insufficient Evidence]

Reported Doses

Safety/efficacy may not be established; reported doses may be derived from limited or potentially inadequate studies w/ variable regimens, multi-ingredient products, or where concentration of active ingredients may vary widely

Effectiveness Ratings

[see Herb & Supplement Effectiveness Rating Definitions table]

anxiety

[Insufficient Evidence]
Dose: 3 gtt peppermint oil diffused for inhaled aromatherapy x1h

athletic performance

[Insufficient Evidence]
Dose: 0.05 mL peppermint oil/500 mL water PO x1 given 30min before exercise

barium enema-related colonic spasm

[Possibly Effective]
Info: peppermint oil added to barium enema preparation

dental plaque

[Insufficient Evidence]
Dose: 10 mL (1.6 mg/g mouthwash) swish/spit bid

dysmenorrhea

[Insufficient Evidence]
Dose: 561 mg PO qd x3 days; Start: 1st day of menstruation

dyspepsia

[Possibly Effective]
Dose: 90 mg PO bid-tid; Alt: 16.7 mg/1 mL PO tid

endoscopy-assoc. adverse effects

[Possibly Effective]
Dose: 187 mg ER PO x1 given 4h before procedure

esophageal spasm

[Insufficient Evidence]
Dose: 5 gtt peppermint oil/10 mL water PO x1

fatigue

[Insufficient Evidence]
Dose: 3 gtt peppermint oil diffused for inhaled aromatherapy x20min qhs

halitosis

[Insufficient Evidence]
Dose: apply 0.5% peppermint oil topically bid; Info: used w/ tea tree oil and lemon oil

IBS

[Likely Effective]
Dose: 180-450 mg PO bid-qid

insomnia

[Insufficient Evidence]
Dose: 3 gtt peppermint oil diffused for inhaled aromatherapy x20min qhs

menopausal sx

[Insufficient Evidence]
Dose: apply 2 gtt peppermint oil topically to hand and arm for aromatherapy massage x30min 2x/wk

migraine, acute

[Insufficient Evidence]
Dose: apply 1-2 gtt (1.5% peppermint oil) intranasally x1 at start of migraine

nausea/vomiting, chemo-related, adult pts

[Possibly Effective]
Dose: 40 gtt peppermint oil/20 mL water PO q8h after chemo; Alt: 2 gtt peppermint oil diffused for inhaled aromatherapy x30min; apply 1 gtt peppermint oil topically below nose tid

nausea/vomiting, chemo-related, peds pts

[Possibly Effective]
Dose: 2 gtt peppermint oil/80 mL water diffused for inhaled aromatherapy x30min before chemo, then cont. 2h and 4h after chemo 1x/wk; Info: used w/ lemon oil

nausea/vomiting, postop

[Insufficient Evidence]
Dose: 10-30% peppermint oil diffused for inhaled aromatherapy x1; Start: 1-4h after surgery

nausea/vomiting, pregnancy-related

[Insufficient Evidence]
Dose: 5% peppermint oil diffused for inhaled aromatherapy q5min prn

nipple fissures

[Possibly Effective]
Dose: apply topically after breastfeeding; Info: products incl. gel, solution, cream

postop ileus

[Insufficient Evidence]
Dose: 20 gtt peppermint oil PO x1 given 4h after surgery, then 20 gtt peppermint oil PO q1h x3 doses

postop pain

[Insufficient Evidence]
Dose: 0.1 mL (10% peppermint oil) diffused for inhaled aromatherapy tid x7 doses; Alt: 5 gtt peppermint oil diffused for inhaled aromatherapy x1 after surgery

postop sleep disturbance

[Insufficient Evidence]
Dose: 0.1 mL (10% peppermint oil) diffused for inhaled aromatherapy tid x7 doses

pressure ulcer

[Possibly Effective]
Dose: apply 0.2% gel topically tid

pruritus

[Insufficient Evidence]
Dose: apply 5% peppermint oil in petrolatum topically bid; Alt: apply 3.6% gel topically x24h covered w/ gauze; apply 0.5% peppermint oil topically bid

stress

[Insufficient Evidence]
Dose: 5 gtt peppermint oil diffused for inhaled aromatherapy x1

tension headache

[Possibly Effective]
Dose: apply 10% peppermint oil topically x1

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