MSM

Reported Uses

• NOTE: see Herb & Supplement Effectiveness Rating Definitions table
• aging skin [Insufficient Evidence]
• allergic rhinitis [Insufficient Evidence]
• Alzheimer dz [Insufficient Evidence]
• androgenic alopecia [Insufficient Evidence]
• arthralgia, aromatase inhibitor-induced [Insufficient Evidence]
• asthma [Insufficient Evidence]
• athletic performance [Insufficient Evidence]
• chronic fatigue syndrome [Insufficient Evidence]
• chronic venous insufficiency [Possibly Ineffective]
• COPD [Insufficient Evidence]
• constipation [Insufficient Evidence]
• diabetes [Insufficient Evidence]
• dyslipidemia [Insufficient Evidence]
• dyspepsia [Insufficient Evidence]
• exercise-induced muscle damage [Insufficient Evidence]
• hangover [Insufficient Evidence]
• hemorrhoids [Insufficient Evidence]
• insect bite [Insufficient Evidence]
• interstitial cystitis [Insufficient Evidence]
• knee pain [Insufficient Evidence]
• muscle cramps [Insufficient Evidence]
• obesity [Insufficient Evidence]
• osteoarthritis [Possibly Effective]
• osteoporosis [Insufficient Evidence]
• periodontitis [Insufficient Evidence]
• peripheral neuropathy, chemo-induced [Insufficient Evidence]
• pneumonia [Insufficient Evidence]
• postop pain [Insufficient Evidence]
• rheumatoid arthritis [Insufficient Evidence]
• rosacea [Insufficient Evidence]
• scleroderma [Insufficient Evidence]
• striae gravidarum (stretch marks) [Insufficient Evidence]
• SLE [Insufficient Evidence]
• temporomandibular disorder [Insufficient Evidence]
• tendinopathy [Insufficient Evidence]
• wound healing [Insufficient Evidence]

Reported Doses

Safety/efficacy may not be established; reported doses may be derived from limited or potentially inadequate studies w/ variable regimens, multi-ingredient products, or where concentration of active ingredients may vary widely

Effectiveness Ratings

[see Herb & Supplement Effectiveness Rating Definitions table]

aging skin

[Insufficient Evidence]

Dose: 1-3 g PO qd

allergic rhinitis

[Insufficient Evidence]

Dose: 2.6 g PO qd

arthralgia, aromatase inhibitor-induced

[Insufficient Evidence]

Dose: 200 mg PO qd

exercise-induced muscle damage

[Insufficient Evidence]

Dose: 50 mg/kg/dose in 200 mL water PO qd; Start: 10 days before exercise

hemorrhoids

[Insufficient Evidence]

Dose: apply gel topically qd x14 days

knee pain

[Insufficient Evidence]

Dose: 1000 mg PO bid

osteoarthritis

[Possibly Effective]

Dose: 1.5-6 g/day PO divided bid-tid; Alt: 500 mg PO qd; Info: used w/ or w/o glucosamine

peripheral neuropathy, chemo-induced

[Insufficient Evidence]

Dose: 200 mg PO qd

postop pain

[Insufficient Evidence]

Dose: 550 mg PO qd

rosacea

[Insufficient Evidence]

Dose: apply cream topically bid