Selected Drugs Clear All
MultiCheck Results
- 10
Interactions
Avoid/Use Alternative |
||
|
diazepam rectal
(generic) + Libervant
(diazepam transmucosal) |
||
Avoid/Use Alternativediazepam + diazepam use alternative or monitor respiratory rate; use lowest effective doses and shortest duration of concomitant tx: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment (additive effects, duplicate therapy) |
||
|
diazepam rectal
(generic) + Sezaby
(phenobarbital) |
||
Avoid/Use Alternativediazepam + phenobarbital use alternative or monitor respiratory rate; use lowest effective doses and shortest duration of concomitant tx: combo may decr. diazepam levels, efficacy; may incr. risk of profound CNS and respiratory depression, psychomotor impairment (hepatic metabolism induced; additive effects) |
||
|
Libervant
(diazepam transmucosal) + Sezaby
(phenobarbital) |
||
Avoid/Use Alternativediazepam + phenobarbital use alternative or monitor respiratory rate; use lowest effective doses and shortest duration of concomitant tx: combo may decr. diazepam levels, efficacy; may incr. risk of profound CNS and respiratory depression, psychomotor impairment (hepatic metabolism induced; additive effects) |
||
Monitor/Modify Tx |
||
|
diazepam rectal
(generic) + Equetro
(carbamazepine) |
||
Monitor/Modify Txdiazepam + carbamazepine monitor respiratory rate; use lowest effective doses and shortest duration of concomitant tx: combo may decr. diazepam levels, efficacy; may incr. risk of profound CNS and respiratory depression, psychomotor impairment (hepatic metabolism induced; additive effects) |
||
|
diazepam rectal
(generic) + valproate sodium
(generic) |
||
Monitor/Modify Txdiazepam + valproic acid monitor respiratory rate, use lowest effective doses and shortest duration of concomitant tx: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment (additive effects) |
||
|
Equetro
(carbamazepine) + Libervant
(diazepam transmucosal) |
||
Monitor/Modify Txcarbamazepine + diazepam monitor respiratory rate; use lowest effective doses and shortest duration of concomitant tx: combo may decr. diazepam levels, efficacy; may incr. risk of profound CNS and respiratory depression, psychomotor impairment (hepatic metabolism induced; additive effects) |
||
|
Equetro
(carbamazepine) + Sezaby
(phenobarbital) |
||
Monitor/Modify Txcarbamazepine + phenobarbital monitor levels of both drugs, BP, respiratory rate: combo may decr. levels of both drugs, efficacy; may incr. risk of CNS and respiratory depression, psychomotor impairment, hypotension, including syncope (hepatic metabolism induced; additive effects) |
||
|
Equetro
(carbamazepine) + valproate sodium
(generic) |
||
Monitor/Modify Txcarbamazepine + valproic acid monitor levels of both drugs: combo may decr. valproic acid levels, efficacy; may incr. carbamazepine active metabolite levels, risk of CNS depression, psychomotor impairment, other adverse effects (UGT induced; epoxide hydrolase inhibited, additive effects) |
||
|
Libervant
(diazepam transmucosal) + valproate sodium
(generic) |
||
Monitor/Modify Txdiazepam + valproic acid monitor respiratory rate, use lowest effective doses and shortest duration of concomitant tx: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment (additive effects) |
||
|
Sezaby
(phenobarbital) + valproate sodium
(generic) |
||
Monitor/Modify Txphenobarbital + valproic acid monitor levels of both drugs, ECG, respiratory rate: combo may incr. phenobarbital levels, risk of CNS and respiratory depression, psychomotor impairment, QT prolongation, cardiac arrhythmias, other adverse effects; may decr. valproic acid levels, efficacy (hepatic metabolism possibly inhibited, additive effects; hepatic metabolism possibly induced, UGT possibly induced) |
||
Additional Considerations |
||
|
carbamazepine
in Equetro
|
||
|
add MAO inhibitor to Interaction Check if recent (14 days) use some formulations of carbamazepine contain sorbitol |
||