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Interaction Check

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Selected Drugs Clear All

  • remove Aleve Headache Pain
    naproxen sodium
  • remove Balfaxar (prothrombin complex concentrate (human)-lans)
    prothrombin complex concentrate (human)
  • remove buprenorphine transdermal
    generic

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Monitor/Modify Tx

Smiley face Smiley face Aleve Headache Pain (naproxen sodium) + Balfaxar (prothrombin complex concentrate (human)-lans) (prothrombin complex concentrate (human))

Monitor/Modify Tx


naproxen + prothrombin complex concentrate (human)

monitor thrombosis s/sx; use lowest effective naproxen dose, shortest effective tx duration: combo may incr. risk of thromboembolism (additive effects)

Additional Considerations

Smiley face Smiley face buprenorphine in buprenorphine transdermal

consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use

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