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Interaction Check

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Selected Drugs Clear All

  • remove Trilafon
    perphenazine
  • remove Vicks ZzzQuil Night Pain
    acetaminophen/ diphenhydramine
  • remove Vicks ZzzQuil Soothing Sleep
    diphenhydramine

multicheck MultiCheck Results - 3 Interactions

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face Vicks ZzzQuil Night Pain (acetaminophen/ diphenhydramine) + Vicks ZzzQuil Soothing Sleep (diphenhydramine)

Avoid/Use Alternative


diphenhydramine + diphenhydramine

avoid combo: combo may incr. risk of CNS depression, psychomotor impairment, anticholinergic adverse effects (additive effects; duplicate therapy)

Monitor/Modify Tx

Smiley face Smiley face Trilafon (perphenazine) + Vicks ZzzQuil Night Pain (acetaminophen/ diphenhydramine)

Monitor/Modify Tx


perphenazine + diphenhydramine

consider decr. dose of one or both drugs: combo may incr. perphenazine levels, risk of CNS depression, psychomotor impairment, anticholinergic and other adverse effects (hepatic metabolism inhibited, additive effects)

Smiley face Smiley face Trilafon (perphenazine) + Vicks ZzzQuil Soothing Sleep (diphenhydramine)

Monitor/Modify Tx


perphenazine + diphenhydramine

consider decr. dose of one or both drugs: combo may incr. perphenazine levels, risk of CNS depression, psychomotor impairment, anticholinergic and other adverse effects (hepatic metabolism inhibited, additive effects)

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