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Interaction Check

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Selected Drugs Clear All

  • remove Alsuma
    sumatriptan
  • remove Stadol NS
    butorphanol nasal

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face Alsuma (sumatriptan) + Stadol NS (butorphanol nasal)

Avoid/Use Alternative


sumatriptan + butorphanol

use alternative or monitor respiratory rate, serotonin syndrome sx, especially during initiation/titration; decr. dose of one or both drugs, use lowest effective doses and shortest duration of concomitant tx: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment, serotonin syndrome (additive effects)

Additional Considerations

Smiley face Smiley face butorphanol in Stadol NS

consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use

Smiley face Smiley face sumatriptan in Alsuma

add MAO inhibitor to Interaction Check if recent (14 days) use

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