Selected Drugs Clear All
MultiCheck Results
- 31
Interactions
Avoid/Use Alternative |
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propofol
(generic) + sodium oxybate
(generic) |
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Avoid/Use Alternativepropofol + oxybate use alternative or monitor resp. rate; decr. dose of one or both drugs: combo may incr. risk of profound CNS and resp. depression, psychomotor impairment, hypotension, syncope (additive effects) |
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Ryanodex
(dantrolene) + sodium oxybate
(generic) |
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Avoid/Use Alternativedantrolene + oxybate use alternative or monitor resp. rate; decr. dose of one or both drugs: combo may incr. risk of profound CNS and resp. depression, psychomotor impairment, hypotension, syncope (additive effects) |
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sodium oxybate
(generic) + Trileptal
(oxcarbazepine) |
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Avoid/Use Alternativeoxybate + oxcarbazepine use alternative or monitor resp. rate; decr. dose of one or both drugs: combo may incr. risk of profound CNS and resp. depression, psychomotor impairment, hypotension, syncope (additive effects) |
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Monitor/Modify Tx |
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Aloxi
(palonosetron) + Gimoti
(metoclopramide nasal) |
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Monitor/Modify Txpalonosetron + metoclopramide monitor serotonin syndrome sx, especially during initiation/titration: combo may incr. risk of serotonin syndrome (additive effects) |
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Amethyst
(levonorgestrel/ ethinyl estradiol) + Gimoti
(metoclopramide nasal) |
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Monitor/Modify Txethinyl estradiol (contraceptive) + metoclopramide monitor BP: combo may incr. risk of HTN (additive effects) |
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Amethyst
(levonorgestrel/ ethinyl estradiol) + lakritze
(licorice (Glycyrrhiza glabra)) |
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Monitor/Modify Txethinyl estradiol (contraceptive) + licorice monitor BP w/ large amounts of licorice: combo may incr. risk of HTN (additive effects) |
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brimonidine topical
(generic) + propofol
(generic) |
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Monitor/Modify Txbrimonidine topical + propofol monitor BP, resp. rate; consider decr. dose of one or both drugs: combo may incr. risk of CNS and resp. depression, psychomotor impairment, severe hypotension, incl. orthostasis (additive effects) |
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Gimoti
(metoclopramide nasal) + lakritze
(licorice (Glycyrrhiza glabra)) |
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Monitor/Modify Txmetoclopramide + licorice monitor BP w/ large amounts of licorice: combo may incr. risk of HTN (additive effects) |
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propofol
(generic) + Ryanodex
(dantrolene) |
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Monitor/Modify Txpropofol + dantrolene monitor resp. rate; consider decr. dose of one or both drugs: combo may incr. risk of CNS and resp. depression, psychomotor impairment (additive effects) |
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propofol
(generic) + solifenacin
(generic) |
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Monitor/Modify Txpropofol + solifenacin monitor resp. rate; consider decr. dose of one or both drugs: combo may incr. risk of CNS and resp. depression, psychomotor impairment (additive effects) |
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propofol
(generic) + Trileptal
(oxcarbazepine) |
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Monitor/Modify Txpropofol + oxcarbazepine monitor resp. rate; consider decr. dose of one or both drugs: combo may incr. risk of CNS and resp. depression, psychomotor impairment; may alter seizure control (additive effects; antagonistic effects, propofol may decr. seizure threshold) |
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Caution Advised |
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Amethyst
(levonorgestrel/ ethinyl estradiol) + Ryanodex
(dantrolene) |
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Caution Advisedethinyl estradiol (contraceptive) + dantrolene caution advised, especially in pts >35 yo: combo may incr. risk of hepatotoxicity (additive effects) |
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Augmentin ES-600
(amoxicillin/ clavulanate) + Trileptal
(oxcarbazepine) |
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Caution Advisedamoxicillin + oxcarbazepine caution advised if seizure disorder use, especially w/ high amoxicillin doses or concomitant renal impairment: combo may alter seizure control (antagonistic effects, amoxicillin may decr. seizure threshold) |
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brimonidine topical
(generic) + Ryanodex
(dantrolene) |
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Caution Advisedbrimonidine topical + dantrolene caution advised: combo may incr. risk of CNS depression, psychomotor impairment (additive effects) |
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brimonidine topical
(generic) + solifenacin
(generic) |
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Caution Advisedbrimonidine topical + solifenacin caution advised: combo may incr. risk of CNS depression, psychomotor impairment (additive effects) |
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brimonidine topical
(generic) + Trileptal
(oxcarbazepine) |
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Caution Advisedbrimonidine topical + oxcarbazepine caution advised: combo may incr. risk of CNS depression, psychomotor impairment (additive effects) |
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Ryanodex
(dantrolene) + solifenacin
(generic) |
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Caution Adviseddantrolene + solifenacin caution advised: combo may incr. risk of CNS depression, psychomotor impairment (additive effects) |
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Ryanodex
(dantrolene) + Trileptal
(oxcarbazepine) |
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Caution Adviseddantrolene + oxcarbazepine caution advised: combo may incr. risk of CNS depression, psychomotor impairment (additive effects) |
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solifenacin
(generic) + Trileptal
(oxcarbazepine) |
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Caution Advisedsolifenacin + oxcarbazepine caution advised: combo may incr. risk of CNS depression, psychomotor impairment (additive effects) |
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Additional Considerations |
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lamivudine
|
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avoid combo of lamivudine oral solution w/ oral products containing sorbitol; may give lamivudine tab formulation or monitor virologic response more frequently if combo cannot be avoided; sorbitol may decr. bioavailability of lamivudine, resulting in decr. levels, efficacy |
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