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Interaction Check

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Selected Drugs Clear All

  • remove Carduus marianus
    milk thistle (Silybum marianum)
  • remove Dengvaxia
    dengue tetravalent vaccine, live (DEN4CYD)
  • remove Lazanda
    fentanyl nasal
  • remove oil of peppermint
    peppermint (Mentha x piperita)
  • remove Salonpas Hot
    capsaicin topical

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Monitor/Modify Tx

Smiley face Smiley face Lazanda (fentanyl nasal) + oil of peppermint (peppermint (Mentha x piperita))

Monitor/Modify Tx


fentanyl + peppermint

monitor respiratory rate, consider decr. fentanyl dose: combo may incr. fentanyl levels, risk of CNS and respiratory depression, psychomotor impairment, other adverse effects (hepatic metabolism inhibited)

Additional Considerations

Smiley face Smiley face fentanyl in Lazanda

consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use

add MAO inhibitor to Interaction Check if recent (14 days) use

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