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Interaction Check

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Selected Drugs Clear All

  • remove Children's Robitussin Cough & Cold CF
    dextromethorphan/ phenylephrine/ guaifenesin
  • remove Priftin
    rifapentine
  • remove Triumeq
    abacavir/ dolutegravir/ lamivudine

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face Priftin (rifapentine) + Triumeq (abacavir/ dolutegravir/ lamivudine)

Avoid/Use Alternative


rifapentine + dolutegravir

avoid combo if rifapentine daily or dolutegravir bid use; monitor virologic response w/ rifapentine weekly and dolutegravir daily: combo may decr. dolutegravir levels, efficacy (hepatic metabolism induced, P-gp-mediated transport induced, UGT induced)

Additional Considerations

Smiley face Smiley face phenylephrine in Children's Robitussin Cough & Cold CF

add MAO inhibitor to Interaction Check if recent (14 days) use

Smiley face Smiley face dextromethorphan in Children's Robitussin Cough & Cold CF

add MAO inhibitor to Interaction Check if recent (14 days) use

Smiley face Smiley face abacavir in Triumeq

some formulations of abacavir contain sorbitol

Smiley face Smiley face lamivudine in Triumeq

avoid combo of lamivudine oral solution with oral products containing sorbitol; may give lamivudine tab formulation or monitor virologic response more frequently if combo cannot be avoided; sorbitol may decr. bioavailability of lamivudine, resulting in decr. levels, efficacy

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