epocrates logo
epocrates logo
epocrates logo
  • 0

Interaction Check

epocrates logo

Sign in to access our clinical decision support tools

Sign in Create Account

Selected Drugs Clear All

  • remove rifabutin
    generic
  • remove Velivet
    desogestrel/ ethinyl estradiol

multicheck MultiCheck Results - 2 Interactions

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face rifabutin (generic) + Velivet (desogestrel/ ethinyl estradiol)

Avoid/Use Alternative


rifabutin + desogestrel (contraceptive)

use additional non-hormonal or alternative contraception during and x28 days after rifabutin tx: combo may decr. desogestrel levels, contraceptive efficacy (hepatic metabolism induced)

rifabutin + ethinyl estradiol (contraceptive)

use additional non-hormonal or alternative contraception during and x28 days after rifabutin tx: combo may decr. ethinyl estradiol levels, contraceptive efficacy (hepatic metabolism induced, UGT induced, P-gp-mediated transport possibly induced)

Help
FDA Reporting Form
 
Download Epocrates from the App Store Download Epocrates from the Play Store
About Us Features Business Solutions Help & Feedback
© 2026 epocrates, Inc.    Terms of Use Privacy Policy Editorial Policy Do Not Sell or Share My Information