Photosensitizing Agents

Special Note

[background]

Info: photosensitizing agents may incr. risk of photosensitivity reaction, including phototoxicity and photoallergy; patients to avoid or limit natural or artificial light and use sun protective measures per pkg insert recommendations; certain photosensitizing agents are used in the setting of photodynamic therapy for therapeutic benefit

allergy/cold/ENT

[antihistamines, 1st generation]

promethazine

alternative medicine

[miscellaneous]

dong quai (Angelica sinensis); St. John's wort (Hypericum perforatum)

antimicrobial

[antifungals]

griseofulvin; ketoconazole topical; rezafungin; terbinafine; voriconazole

[quinolones]

ciprofloxacin; levofloxacin; moxifloxacin; ofloxacin

[sulfonamides/sulfones]

dapsone; sulfadiazine; sulfamethoxazole

[tetracyclines/derivatives]

demeclocycline; doxycycline; eravacycline; minocycline; omadacycline; sarecycline; tetracycline; tigecycline

cardiovascular

[antiarrhythmics]

amiodarone

[diuretics, loop]

furosemide

[diuretics, thiazide]

chlorothiazide; chlorthalidone; hydrochlorothiazide; indapamide; metolazone

dermatologic

[antimicrobials]

benzoyl peroxide topical; doxycycline; ketoconazole topical; griseofulvin; minocycline; tetracycline; sarecycline

[antineoplastics]

alitretinoin topical; aminolevulinic acid topical; bexarotene; bexarotene topical; fluorouracil topical; imiquimod topical

[antipsoriatics]

acitretin; methoxsalen; tazarotene topical

[folate analogs]

methotrexate

[keratolytics]

ammonium lactate topical; benzoyl peroxide topical; coal tar topical; salicylic acid topical

[porphyrins]

aminolevulinic acid topical

[retinoids]

acitretin; adapalene topical; alitretinoin topical; bexarotene; bexarotene topical; isotretinoin; tazarotene topical; tretinoin topical; trifarotene topical

emergency

[antidotes]

hydroxocobalamin; methylene blue injection

endocrine

[cyclic pyranopterin monophosphates]

fosdenopterin

[retinoids]

palovarotene

[sulfonylureas]

glimepiride; glipizide; glyburide

gastrointestinal

[folate analogs]

methotrexate

[phenothiazines]

chlorpromazine, perphenazine, prochlorperazine, prochlorperazine rectal, promethazine, promethazine rectal

[salicylates]

balsalazide; mesalamine; mesalamine rectal; olsalazine; sulfasalazine

musculoskeletal

[muscle relaxants]

dantrolene

[NSAIDs]

nabumetone; oxaprozin

oncologic

[antiandrogens]

bicalutamide

[CD19 inhibitors]

loncastuximab tesirine

[EGFR inhibitors]

cetuximab; necitumumab; panitumumab

[EGFR inhibitors and kinase inhibitors]

lazertinib

[EGFR inhibitors and MET inhibitors]

amivantamab

[folate analogs]

methotrexate

[kinase inhibitors]

alectinib; avapritinib; avutometinib, brigatinib; capmatinib; ceritinib; cobimetinib; crizotinib; defactinib, ensartinib, pexidartinib; ripretinib; taletrectinib; tovorafenib; vandetanib; vemurafenib

[PARP inhibitors]

rucaparib

[porphyrins]

porfimer

[purine analogs]

mercaptopurine

[pyrimidine analogs]

fluorouracil topical

[retinoids]

alitretinoin topical; bexarotene; bexarotene topical; tretinoin

ophthalmologic

[porphyrins]

verteporfin

psychiatric

[antipsychotics]

chlorpromazine; fluphenazine; perphenazine; prochlorperazine; thioridazine; thiothixene; trifluoperazine

[TCAs]

amitriptyline; amoxapine; clomipramine; desipramine; doxepin; imipramine; nortriptyline; protriptyline; trimipramine

pulmonary

[pyridones]

pirfenidone

rheumatologic

[DMARDs]

methotrexate, sulfasalazine

[NSAIDs]

nabumetone; oxaprozin