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JAMA Psychiatry

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Small mental health signal after abortion fades with closer analysis

Danish registry data found no robust increase in psychotropic medication use after either medication or procedural abortion once multiple comparisons were considered. . .

Lancet

Orals showdown: GLP-1 tops SGLT2 on A1c in diabetes

A head-to-head trial between these oral classes had a clear winner, but side effects played a complicating role. . .

Drug pipeline

Dual bispecific combo cuts myeloma progression risk by 89%

Phase 3 topline results suggest teclistamab plus talquetamab could move dual-targeted, off-the-shelf immunotherapy earlier in the treatment pathway. . .

Survey

One in six young adults handle no basic healthcare tasks

Only about half schedule appointments or decide when care is needed, according to a survey of parents. . .

JAMA Netw Open

Clinician recommendation may unlock RSV protection for hesitant families

Pregnant women and parents generally favored maternal RSV vaccination, but information gaps and safety concerns remained major barriers. . .

Proc Natl Acad Sci U S A

Sweat patch reads levodopa levels without a blood draw

A fingertip sensor estimated blood levodopa with close agreement to lab assays, an early step toward objective at-home dose timing. . .

Company news

FDA approves first-in-class ADHD treatment

Simtriyo (centanafadine) is a once-daily stimulant that targets norepinephrine, dopamine, and serotonin. . .

JAMA Netw Open

GLP-1s tied to fewer fragility fractures in type 2 diabetes

The lower risk held even though weight loss usually raises fracture odds, and it did not extend to patients without diabetes. . .

JAMA Netw Open

Morning or afternoon flu shot? It likely doesn’t matter

A study of nearly 16 million adults found no meaningful difference in influenza risk based on the hour of vaccination. . .

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