J Am Coll Cardiol
Stable coronary artery disease: Which symptoms predict success from PCI?
Symptom nature was a powerful predictor of PCI efficacy, in this secondary analysis of the placebo-controlled ORBITA-2 trial. Rose angina and guideline-based typical angina strongly predicted PCI efficacy. However, symptom severity and nature correlated poorly with disease severity.
- Evidence from the placebo-controlled ORBITA-2 trial had shown that residual symptoms persisted in many patients post PCI.
- The ORBITA smartphone app was used to collect symptom severity and nature pre-randomization; the Rose angina questionnaire assessed symptoms and quality of life.
- Quantitative coronary angiography, stress echo, fractional flow reserve, and instantaneous wave-free ratio were used to assess disease severity.
Source:
Simader FA, et al. (2024, May 15). J Am Coll Cardiol. Symptoms as a Predictor of the Placebo-Controlled Efficacy of PCI in Stable Coronary Artery Disease. https://pubmed.ncbi.nlm.nih.gov/38759906/