JAMA Dermatol
Eczema: Is an antihypertensive drug the cause?
Calcium channel blockers and diuretics were among the antihypertensive classes with the highest hazard rates for eczema in older adults, while angiotensin-converting enzyme inhibitors and beta-blockers showed the lowest hazard rates, in this population-based cohort study. Any antihypertensive drug use was linked to a 29% increase in the rate of eczematous dermatitis diagnosis.
- This UK-based longitudinal primary care population cohort study (N=1.5 M, 54% female) included patients 60+ years old with and without eczema at baseline, and correlated eczema with first prescriptions of antihypertensive drugs over a median follow-up duration of 6 years.
- The overall prevalence of eczema was 6.7% during the study.
- Although mechanisms underlying the association are not clear, it should be considered in the differential for older patients with eczema following initiation of antihypertensive agents.
Source:
Ye M, et al. (2024, May 22). JAMA Dermatol. Antihypertensive Medications and Eczematous Dermatitis in Older Adults. https://pubmed.ncbi.nlm.nih.gov/38776099/