JAMA Netw Open

Home BP monitoring, self-titration of meds linked to long-term BP reduction

May 14, 2024

BP self-monitoring plus self-titration of antihypertensive medication reduced BP in the longer term compared with usual care, without increasing health care use or adverse events. The findings of this secondary analysis suggest that an easy-to-implement self-management intervention has the potential to improve long-term control of hypertension in routine clinical practice.

The randomized, unblinded ADAMPA (Impact of Self-Monitoring of Blood Pressure and Self-Titration of Medication in the Control of Hypertension) study included participants ≥40 years of age with systolic BP (SBP) >145 mm Hg and/or diastolic BP (DBP) >90 mm Hg. Participants were randomized 1:1 to usual care vs. an individualized, prearranged plan based on BP self-monitoring plus medication self-titration.

Among 312 participants in the main trial, data on BP measurements at 24 months were available for 219 patients (111 in the intervention group, 108 in the control group). Mean age was 64.3 years; 54.8% were female; mean SBP was 155.6 mm Hg, and mean DBP was 90.8 mm Hg. After a median follow-up was 23.8 months, the adjusted mean difference in SBP and DBP was −3.4 mm Hg and −2.5 mm Hg, respectively. No between-group differences were observed in behaviors, quality of life, use of health services, or adverse events.

Source:

Martínez-Ibáñez P, et al. (2024, May 10). JAMA Netw Open. Long-Term Effect of Home Blood Pressure Self-Monitoring Plus Medication Self-Titration for Patients With Hypertension: A Secondary Analysis of the ADAMPA Randomized Clinical Trial. https://pubmed.ncbi.nlm.nih.gov/38728033/