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Journal Article Synopsis

J Gen Intern Med

New guideline urges caution and customization in benzodiazepine tapering

June 26, 2025

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This joint clinical practice guideline, developed by the American Society of Addiction Medicine and nine partner organizations, uses a modified GRADE methodology and expert consensus to guide clinicians in tapering benzodiazepines (BZDs) across diverse care settings.

Key recommendations:

  • Assess risk–benefit continuously: Tapering is appropriate when harms of ongoing BZD use exceed benefits.
  • Avoid abrupt cessation: Especially in physically dependent patients, sudden discontinuation can lead to serious withdrawal.
  • Tailor taper plans: Individualize based on patient needs, clinical response, and context.
  • Engage patients: Shared decision-making and clear communication are essential.
  • Support the process: Psychosocial interventions can improve tapering outcomes.

Source:

Brunner E, et al. (2025, June 17). J Gen Intern Med. Joint Clinical Practice Guideline on Benzodiazepine Tapering: Considerations When Risks Outweigh Benefits. https://pubmed.ncbi.nlm.nih.gov/40526204/

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