Lancet
Once-weekly basal insulin performs as well as once-daily glargine in trial
May 10, 2023

In the phase 3a ONWARDS 4 trial involving 582 adults with long-standing type 2 diabetes on a basal-bolus regimen, once-weekly icodec led to similar improvements in glycemic control at 26 weeks, with fewer basal insulin injections, lower bolus insulin dose, and no increase in hypoglycemic events compared with once-daily glargine U100.
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