NIH

Zebra of the Week: Late-onset retinal degeneration

June 9, 2025

Late-onset retinal degeneration is an inherited retinal dystrophy characterized by delayed dark adaptation and nyctalopia and drusen deposits presenting in adulthood, followed by cone and rod degeneration in the sixth decade of life, which leads to central vision loss. Anterior segment features such as peripupillary iris transillumination defects and abnormally long anterior zonular insertions are also seen. Choroidal neovascularization and glaucoma may occur in the late stages of the disease.

Source:

(Accessed 2025, June 6). NIH. Late-onset retinal degeneration. https://rarediseases.info.nih.gov/diseases/4357/late-onset-retinal-degeneration