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Ixchiq
chikungunya vaccine, live
Adult Dosing .
Dosage forms: INJ
Withdrawn from US Market
- [January 2026]
- Info: voluntarily withdrawn following FDA approval suspension due to severe neurologic and cardiac adverse events
Peds Dosing .
- Dosage forms: --
Withdrawn from US Market
- [January 2026]
- Info: voluntarily withdrawn following FDA approval suspension due to severe neurologic and cardiac adverse events
Contraindications / Cautions .
- hypersensitivity to drug or ingredient
- immunocompromised patients
- caution: patients 65 yo and older with chronic conditions
- caution: illness, acute moderate-severe
Drug Interactions .
Overview
chikungunya vaccine, live
live vaccine
- live vaccine
- Withdrawn from US Market
Contraindicated
Avoid/Use Alternative
Monitor/Modify Tx
Adverse Reactions .
Serious Reactions
- hypersensitivity reaction
- chikungunya-like reaction, prolonged
- chikungunya-like reaction, severe
- encephalitis
Common Reactions
- headache
- fatigue
- leukopenia
- neutropenia
- myalgia
- lymphopenia
- arthralgia
- fever
- nausea
- injection site reaction
- rash
- chills
- diarrhea
- back pain
- lymphadenopathy
Safety/Monitoring .
Monitoring Parameters
no routine tests recommended
Pregnancy/Lactation .
Pregnancy
Clinical Summary
weigh risk/benefit during pregnancy; monitor neonate for chikungunya disease x7 days after birth if gestational parent received chikungunya vaccine <14 days before birth; inadequate human data available; no known risk of fetal harm based on animal data at recommended human dose; theoretical risk of chikungunya virus transmission based on human data in infected pregnant patients with viremia
Pregnancy Registry
enroll patients or encourage patients to enroll in Ixchiq Pregnancy Registry at 1-855-417-6214
Lactation
Clinical Summary
weigh risk/benefit while breastfeeding; no human data available to assess risk of infant harm or effects on milk production
Pharmacology .
Metabolism: for chikungunya vaccine: other; CYP450: unknown
Excretion: for chikungunya vaccine: other; Half-life: unknown
Subclass: Chikungunya Vaccines ; Travel Vaccines
Mechanism of Action
for chikungunya vaccine: exact mechanism of action unknown; induces antibody formation
Formulary .
No Formulary Selected
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