Isovue

Overview

iopamidol

contrast agent

• lowers seizure threshold
• nephrotoxicity
• thrombogenic effects

• avoid radioactive iodine during and up to 6wk after iopamidol tx; iopamidol may decr. thyroid uptake of radioactive iodine, efficacy

Contraindicated

• betamethasone
Isovue (iopamidol)

+

betamethasone

1 interaction

Contraindicated

iopamidol + betamethasone

contraindicated if intrathecal iopamidol use and intrathecal betamethasone use; otherwise, caution advised if intrathecal iopamidol use, consider holding betamethasone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• cidofovir
Isovue (iopamidol)

+

cidofovir

1 interaction

Contraindicated

iopamidol + cidofovir

contraindicated; D/C IV iopamidol use at least 7 days prior to cidofovir tx: combo may incr. cidofovir levels, risk of myelosuppression, nephrotoxicity, other adverse effects (additive effects)

• dexamethasone
Isovue (iopamidol)

+

dexamethasone

1 interaction

Contraindicated

iopamidol + dexamethasone

contraindicated if intrathecal iopamidol use and intrathecal dexamethasone use; otherwise, caution advised if intrathecal iopamidol use, consider holding dexamethasone at least 48h before and at least 24h after intrathecal iopamidol; monitor thrombosis s/sx, especially if multiple myeloma use: combo may incr. risk of seizures, thromboembolism (additive effects)

• hydrocortisone
Isovue (iopamidol)

+

hydrocortisone

1 interaction

Contraindicated

iopamidol + hydrocortisone

contraindicated if intrathecal iopamidol use and intrathecal hydrocortisone use; otherwise, caution advised if intrathecal iopamidol use, consider holding hydrocortisone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• methylprednisolone
Isovue (iopamidol)

+

methylprednisolone

1 interaction

Contraindicated

iopamidol + methylprednisolone

contraindicated if intrathecal iopamidol use and intrathecal methylprednisolone use; otherwise, caution advised if intrathecal iopamidol use, consider holding methylprednisolone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

Avoid/Use Alternative

• aldesleukin
Isovue (iopamidol)

+

aldesleukin

1 interaction

Avoid/Use Alternative

iopamidol + aldesleukin

avoid combo; caution advised for several months after aldesleukin tx: combo may incr. risk of nephrotoxicity, seizures; may incr. risk of delayed adverse reactions (additive effects; mechanism unknown)

• amifampridine
Isovue (iopamidol)

+

amifampridine

1 interaction

Avoid/Use Alternative

iopamidol + amifampridine

consider alternative if intrathecal iopamidol use; otherwise, consider holding amifampridine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• amikacin
Isovue (iopamidol)

+

amikacin

1 interaction

Avoid/Use Alternative

iopamidol + amikacin

use alternative or monitor amikacin levels, renal fxn, ototoxicity if IV iopamidol use: combo may incr. amikacin levels, risk of nephrotoxicity, auditory, vestibular, other adverse effects (additive effects)

• amikacin inhaled
Isovue (iopamidol)

+

amikacin inhaled

1 interaction

Avoid/Use Alternative

iopamidol + amikacin inhaled

use alternative or monitor renal fxn, ototoxicity if IV iopamidol use: combo may incr. amikacin levels, risk of nephrotoxicity, auditory, vestibular, other adverse effects (additive effects)

• bumetanide
Isovue (iopamidol)

+

bumetanide

1 interaction

Avoid/Use Alternative

iopamidol + bumetanide

if IV iopamidol use, use alternative or monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• clofarabine
Isovue (iopamidol)

+

clofarabine

1 interaction

Avoid/Use Alternative

iopamidol + clofarabine

avoid IV iopamidol use during 5 day clofarabine tx; monitor CBC, renal fxn, BP: combo may incr. clofarabine levels, risk of serious infection, myelosuppression, nephrotoxicity, hypotension, other adverse effects (additive effects)

• foscarnet
Isovue (iopamidol)

+

foscarnet

1 interaction

Avoid/Use Alternative

iopamidol + foscarnet

use alternative or monitor CBC, renal fxn if IV iopamidol use; caution advised if intrathecal iopamidol use; consider holding foscarnet at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. foscarnet levels, risk of myelosuppression, nephrotoxicity, seizures, other adverse effects (additive effects)

• ganciclovir
Isovue (iopamidol)

+

ganciclovir

1 interaction

Avoid/Use Alternative

iopamidol + ganciclovir

use alternative or monitor CBC, renal fxn if IV iopamidol use; caution advised if intrathecal iopamidol use; consider holding ganciclovir at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. ganciclovir levels, risk of myelosuppression, nephrotoxicity, seizures, other adverse effects (additive effects)

• gentamicin
Isovue (iopamidol)

+

gentamicin

1 interaction

Avoid/Use Alternative

iopamidol + gentamicin

use alternative or monitor gentamicin levels, renal fxn, ototoxicity if IV iopamidol use: combo may incr. gentamicin levels, risk of nephrotoxicity, auditory, vestibular, other adverse effects (additive effects)

• iohexol
Isovue (iopamidol)

+

iohexol

1 interaction

Avoid/Use Alternative

iopamidol + iohexol

avoid combo: combo may incr. risk of nephrotoxicity, thromboembolism, seizures, other adverse effects (additive effects, duplicate tx)

• iomeprol
Isovue (iopamidol)

+

iomeprol

1 interaction

Avoid/Use Alternative

iopamidol + iomeprol

avoid combo: combo may incr. risk of nephrotoxicity, thromboembolism, other adverse effects (additive effects, duplicate tx)

• iopamidol
Isovue (iopamidol)

+

iopamidol

1 interaction

Avoid/Use Alternative

iopamidol + iopamidol

avoid combo: combo may incr. risk of nephrotoxicity, thromboembolism, seizures, other adverse effects (additive effects, duplicate tx)

• mannitol
Isovue (iopamidol)

+

mannitol

1 interaction

Avoid/Use Alternative

iopamidol + mannitol

if IV iopamidol use, use alternative or monitor renal fxn: combo may incr. mannitol levels, risk of nephrotoxicity, neurotoxicity (incl. life-threatening), other adverse effects (additive effects)

• oxaliplatin
Isovue (iopamidol)

+

oxaliplatin

1 interaction

Avoid/Use Alternative

iopamidol + oxaliplatin

use alternative or monitor ECG, CBC, renal fxn, ototoxicity if IV iopamidol use: combo may incr. oxaliplatin levels, risk of QT prolongation, cardiac arrhythmias, serious infection, myelosuppression, nephrotoxicity, auditory, vestibular, other adverse effects (additive effects)

• pentamidine
Isovue (iopamidol)

+

pentamidine

1 interaction

Avoid/Use Alternative

iopamidol + pentamidine

use alternative or monitor renal fxn if IV iopamidol use: combo may incr. risk of nephrotoxicity (additive effects)

• polymyxin B
Isovue (iopamidol)

+

polymyxin B

1 interaction

Avoid/Use Alternative

iopamidol + polymyxin B

if IV iopamidol use, avoid combo: combo may incr. risk of nephrotoxicity (additive effects)

• streptomycin
Isovue (iopamidol)

+

streptomycin

1 interaction

Avoid/Use Alternative

iopamidol + streptomycin

use alternative or monitor renal fxn, ototoxicity if IV iopamidol use: combo may incr. streptomycin levels, risk of nephrotoxicity, auditory, vestibular, other adverse effects (additive effects)

• streptozocin
Isovue (iopamidol)

+

streptozocin

1 interaction

Avoid/Use Alternative

iopamidol + streptozocin

use alternative or monitor renal fxn if IV iopamidol use: combo may incr. risk of nephrotoxicity (additive effects)

• tenofovir disoproxil
Isovue (iopamidol)

+

tenofovir disoproxil

1 interaction

Avoid/Use Alternative

iopamidol + tenofovir disoproxil

use alternative or monitor renal fxn if IV iopamidol use: combo may incr. tenofovir levels, risk of nephrotoxicity, other adverse effects (additive effects)

• tobramycin
Isovue (iopamidol)

+

tobramycin

1 interaction

Avoid/Use Alternative

iopamidol + tobramycin

use alternative or monitor tobramycin levels, renal fxn, ototoxicity if IV iopamidol use: combo may incr. tobramycin levels, risk of nephrotoxicity, auditory, vestibular, other adverse effects (additive effects)

• tobramycin inhaled
Isovue (iopamidol)

+

tobramycin inhaled

1 interaction

Avoid/Use Alternative

iopamidol + tobramycin inhaled

use alternative or monitor renal fxn, ototoxicity if IV iopamidol use: combo may incr. tobramycin levels, risk of nephrotoxicity, auditory, vestibular, other adverse effects (additive effects)

• tranexamic acid
Isovue (iopamidol)

+

tranexamic acid

1 interaction

Avoid/Use Alternative

iopamidol + tranexamic acid

if IV iopamidol use, avoid combo; caution advised if intrathecal iopamidol use; consider holding tranexamic acid at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures, thromboembolism (additive effects)

• vaccinia immune globulin
Isovue (iopamidol)

+

vaccinia immune globulin

1 interaction

Avoid/Use Alternative

iopamidol + vaccinia immune globulin

if IV iopamidol use, use alternative or monitor renal fxn, thrombosis s/sx; use lowest vaccinia immune globulin concentration and infusion rate possible: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• valganciclovir
Isovue (iopamidol)

+

valganciclovir

1 interaction

Avoid/Use Alternative

iopamidol + valganciclovir

use alternative or monitor CBC, renal fxn if IV iopamidol use; caution advised if intrathecal iopamidol use; consider holding valganciclovir at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. ganciclovir levels, risk of myelosuppression, nephrotoxicity, seizures, other adverse effects (additive effects)

Monitor/Modify Tx

• abemaciclib
Isovue (iopamidol)

+

abemaciclib

1 interaction

Monitor/Modify Tx

iopamidol + abemaciclib

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• abrocitinib
Isovue (iopamidol)

+

abrocitinib

1 interaction

Monitor/Modify Tx

iopamidol + abrocitinib

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• acyclovir
Isovue (iopamidol)

+

acyclovir

1 interaction

Monitor/Modify Tx

iopamidol + acyclovir

if IV iopamidol use, monitor renal fxn; caution advised if intrathecal iopamidol use; consider holding acyclovir at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. acyclovir levels, risk of nephrotoxicity, seizures, other adverse effects (additive effects)

• adefovir dipivoxil
Isovue (iopamidol)

+

adefovir dipivoxil

1 interaction

Monitor/Modify Tx

iopamidol + adefovir dipivoxil

if IV iopamidol use, monitor renal fxn: combo may incr. adefovir levels, risk of nephrotoxicity, other adverse effects (renal excretion decreased by nephrotoxic agents, additive effects)

• aflibercept
Isovue (iopamidol)

+

aflibercept

1 interaction

Monitor/Modify Tx

iopamidol + aflibercept

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• alectinib
Isovue (iopamidol)

+

alectinib

1 interaction

Monitor/Modify Tx

iopamidol + alectinib

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• alfentanil
Isovue (iopamidol)

+

alfentanil

1 interaction

Monitor/Modify Tx

iopamidol + alfentanil

caution advised if intrathecal iopamidol use; consider holding alfentanil at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• aliskiren
Isovue (iopamidol)

+

aliskiren

1 interaction

Monitor/Modify Tx

iopamidol + aliskiren

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• amiloride
Isovue (iopamidol)

+

amiloride

1 interaction

Monitor/Modify Tx

iopamidol + amiloride

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• aminocaproic acid
Isovue (iopamidol)

+

aminocaproic acid

1 interaction

Monitor/Modify Tx

iopamidol + aminocaproic acid

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• aminophylline
Isovue (iopamidol)

+

aminophylline

1 interaction

Monitor/Modify Tx

iopamidol + aminophylline

caution advised if intrathecal iopamidol use; consider holding aminophylline at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• amitriptyline
Isovue (iopamidol)

+

amitriptyline

1 interaction

Monitor/Modify Tx

iopamidol + amitriptyline

caution advised if intrathecal iopamidol use; consider holding amitriptyline at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• amoxapine
Isovue (iopamidol)

+

amoxapine

1 interaction

Monitor/Modify Tx

iopamidol + amoxapine

caution advised if intrathecal iopamidol use; consider holding amoxapine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• amoxicillin
Isovue (iopamidol)

+

amoxicillin

1 interaction

Monitor/Modify Tx

iopamidol + amoxicillin

caution advised if intrathecal iopamidol use, especially w/ high amoxicillin doses or concomitant renal impairment; consider holding amoxicillin at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• amphetamine
Isovue (iopamidol)

+

amphetamine

1 interaction

Monitor/Modify Tx

iopamidol + amphetamine

caution advised if intrathecal iopamidol use; consider holding amphetamine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• amphotericin
Isovue (iopamidol)

+

amphotericin

1 interaction

Monitor/Modify Tx

iopamidol + amphotericin

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• ampicillin
Isovue (iopamidol)

+

ampicillin

1 interaction

Monitor/Modify Tx

iopamidol + ampicillin

caution advised if intrathecal iopamidol use, especially w/ high ampicillin doses or concomitant renal impairment; consider holding ampicillin at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• angiotensin II
Isovue (iopamidol)

+

angiotensin II

1 interaction

Monitor/Modify Tx

iopamidol + angiotensin II

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• anthrax immune globulin
Isovue (iopamidol)

+

anthrax immune globulin

1 interaction

Monitor/Modify Tx

iopamidol + anthrax immune globulin

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest anthrax immune globulin infusion rate possible: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• anti-inhibitor coagulant complex
Isovue (iopamidol)

+

anti-inhibitor coagulant complex

1 interaction

Monitor/Modify Tx

iopamidol + anti-inhibitor coagulant complex

if IV iopamidol use, monitor thrombosis s/sx, especially w/ anti-inhibitor coagulant complex dose >100 units/kg: combo may incr. risk of thromboembolism (additive effects)

• antihemophilic factor (factor VIII)/von Willebrand factor complex
Isovue (iopamidol)

+

antihemophilic factor (factor VIII)/ von Willebrand factor complex

1 interaction

Monitor/Modify Tx

iopamidol + antihemophilic factor (factor VIII)/ von Willebrand factor complex

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• apalutamide
Isovue (iopamidol)

+

apalutamide

1 interaction

Monitor/Modify Tx

iopamidol + apalutamide

caution advised if intrathecal iopamidol use; consider holding apalutamide at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• aripiprazole bimonthly injection
Isovue (iopamidol)

+

aripiprazole bimonthly injection

1 interaction

Monitor/Modify Tx

iopamidol + aripiprazole bimonthly injection

caution advised if intrathecal iopamidol use; consider holding aripiprazole at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• aripiprazole lauroxil
Isovue (iopamidol)

+

aripiprazole lauroxil

1 interaction

Monitor/Modify Tx

iopamidol + aripiprazole lauroxil

caution advised if intrathecal iopamidol use; consider holding aripiprazole lauroxil at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• aripiprazole monthly injection
Isovue (iopamidol)

+

aripiprazole monthly injection

1 interaction

Monitor/Modify Tx

iopamidol + aripiprazole monthly injection

caution advised if intrathecal iopamidol use; consider holding aripiprazole at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• aripiprazole oral
Isovue (iopamidol)

+

aripiprazole oral

1 interaction

Monitor/Modify Tx

iopamidol + aripiprazole oral

caution advised if intrathecal iopamidol use; consider holding aripiprazole at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• asciminib
Isovue (iopamidol)

+

asciminib

1 interaction

Monitor/Modify Tx

iopamidol + asciminib

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• asenapine
Isovue (iopamidol)

+

asenapine

1 interaction

Monitor/Modify Tx

iopamidol + asenapine

caution advised if intrathecal iopamidol use; consider holding asenapine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• asparaginase
Isovue (iopamidol)

+

asparaginase

1 interaction

Monitor/Modify Tx

iopamidol + asparaginase

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• aspirin
Isovue (iopamidol)

+

aspirin

1 interaction

Monitor/Modify Tx

iopamidol + aspirin

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• atidarsagene autotemcel
Isovue (iopamidol)

+

atidarsagene autotemcel

1 interaction

Monitor/Modify Tx

iopamidol + atidarsagene autotemcel

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• auranofin
Isovue (iopamidol)

+

auranofin

1 interaction

Monitor/Modify Tx

iopamidol + auranofin

if IV iopamidol use, monitor renal fxn: combo may incr. auranofin levels, risk of nephrotoxicity, other adverse effects (additive effects)

• avatrombopag
Isovue (iopamidol)

+

avatrombopag

1 interaction

Monitor/Modify Tx

iopamidol + avatrombopag

if IV iopamidol use, monitor platelets, thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• axicabtagene ciloleucel
Isovue (iopamidol)

+

axicabtagene ciloleucel

1 interaction

Monitor/Modify Tx

iopamidol + axicabtagene ciloleucel

caution advised if intrathecal iopamidol use: combo may incr. risk of seizures (additive effects)

• axitinib
Isovue (iopamidol)

+

axitinib

1 interaction

Monitor/Modify Tx

iopamidol + axitinib

if IV iopamidol use, monitor renal fxn, thrombosis s/sx: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• azilsartan medoxomil
Isovue (iopamidol)

+

azilsartan medoxomil

1 interaction

Monitor/Modify Tx

iopamidol + azilsartan medoxomil

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• baclofen
Isovue (iopamidol)

+

baclofen

1 interaction

Monitor/Modify Tx

iopamidol + baclofen

caution advised if intrathecal iopamidol use; consider holding baclofen at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• baclofen intrathecal
Isovue (iopamidol)

+

baclofen intrathecal

1 interaction

Monitor/Modify Tx

iopamidol + baclofen intrathecal

caution advised if intrathecal iopamidol use; consider holding baclofen intrathecal at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• balsalazide
Isovue (iopamidol)

+

balsalazide

1 interaction

Monitor/Modify Tx

iopamidol + balsalazide

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• baricitinib
Isovue (iopamidol)

+

baricitinib

1 interaction

Monitor/Modify Tx

iopamidol + baricitinib

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• bazedoxifene
Isovue (iopamidol)

+

bazedoxifene

1 interaction

Monitor/Modify Tx

iopamidol + bazedoxifene

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• benazepril
Isovue (iopamidol)

+

benazepril

1 interaction

Monitor/Modify Tx

iopamidol + benazepril

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• benzphetamine
Isovue (iopamidol)

+

benzphetamine

1 interaction

Monitor/Modify Tx

iopamidol + benzphetamine

caution advised if intrathecal iopamidol use; consider holding benzphetamine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• bevacizumab
Isovue (iopamidol)

+

bevacizumab

1 interaction

Monitor/Modify Tx

iopamidol + bevacizumab

if IV iopamidol use, monitor renal fxn, thrombosis s/sx: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• binimetinib
Isovue (iopamidol)

+

binimetinib

1 interaction

Monitor/Modify Tx

iopamidol + binimetinib

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• bleomycin
Isovue (iopamidol)

+

bleomycin

1 interaction

Monitor/Modify Tx

iopamidol + bleomycin

if IV iopamidol use, monitor renal fxn; decr. bleomycin dose based on CrCl: combo may incr. bleomycin levels, risk of pulmonary toxicities (incl. life-threatening), other adverse effects (renal excretion decreased)

• botulism immune globulin
Isovue (iopamidol)

+

botulism immune globulin

1 interaction

Monitor/Modify Tx

iopamidol + botulism immune globulin

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest botulism immune globulin infusion rate possible: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• brexpiprazole
Isovue (iopamidol)

+

brexpiprazole

1 interaction

Monitor/Modify Tx

iopamidol + brexpiprazole

caution advised if intrathecal iopamidol use; consider holding brexpiprazole at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• brexucabtagene autoleucel
Isovue (iopamidol)

+

brexucabtagene autoleucel

1 interaction

Monitor/Modify Tx

iopamidol + brexucabtagene autoleucel

caution advised if intrathecal iopamidol use: combo may incr. risk of seizures (additive effects)

• brolucizumab
Isovue (iopamidol)

+

brolucizumab

1 interaction

Monitor/Modify Tx

iopamidol + brolucizumab

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• buprenorphine
Isovue (iopamidol)

+

buprenorphine

1 interaction

Monitor/Modify Tx

iopamidol + buprenorphine

caution advised if intrathecal iopamidol use; consider holding buprenorphine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• bupropion
Isovue (iopamidol)

+

bupropion

1 interaction

Monitor/Modify Tx

iopamidol + bupropion

caution advised if intrathecal iopamidol use; consider holding bupropion at least 48h before and at least 24h after intrathecal iopamidol; consider lower bupropion doses: combo may incr. risk of seizures (additive effects)

• busulfan
Isovue (iopamidol)

+

busulfan

1 interaction

Monitor/Modify Tx

iopamidol + busulfan

caution advised if intrathecal iopamidol use; consider holding busulfan at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• butorphanol
Isovue (iopamidol)

+

butorphanol

1 interaction

Monitor/Modify Tx

iopamidol + butorphanol

caution advised if intrathecal iopamidol use; consider holding butorphanol at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• C1 esterase inhibitor
Isovue (iopamidol)

+

C1 esterase inhibitor

1 interaction

Monitor/Modify Tx

iopamidol + C1 esterase inhibitor

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• cabozantinib
Isovue (iopamidol)

+

cabozantinib

1 interaction

Monitor/Modify Tx

iopamidol + cabozantinib

if IV iopamidol use, monitor renal fxn, thrombosis s/sx: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• calaspargase
Isovue (iopamidol)

+

calaspargase

1 interaction

Monitor/Modify Tx

iopamidol + calaspargase

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• candesartan cilexetil
Isovue (iopamidol)

+

candesartan cilexetil

1 interaction

Monitor/Modify Tx

iopamidol + candesartan cilexetil

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• capecitabine
Isovue (iopamidol)

+

capecitabine

1 interaction

Monitor/Modify Tx

iopamidol + capecitabine

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• captopril
Isovue (iopamidol)

+

captopril

1 interaction

Monitor/Modify Tx

iopamidol + captopril

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• carboplatin
Isovue (iopamidol)

+

carboplatin

1 interaction

Monitor/Modify Tx

iopamidol + carboplatin

if IV iopamidol use, monitor CBC, renal fxn, ototoxicity: combo may incr. carboplatin levels, risk of serious infection, myelosuppression, nephrotoxicity, auditory, vestibular, other adverse effects (additive effects)

• carfilzomib
Isovue (iopamidol)

+

carfilzomib

1 interaction

Monitor/Modify Tx

iopamidol + carfilzomib

if IV iopamidol use, monitor renal fxn, thrombosis s/sx: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• cariprazine
Isovue (iopamidol)

+

cariprazine

1 interaction

Monitor/Modify Tx

iopamidol + cariprazine

caution advised if intrathecal iopamidol use; consider holding cariprazine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• cefazolin
Isovue (iopamidol)

+

cefazolin

1 interaction

Monitor/Modify Tx

iopamidol + cefazolin

caution advised if intrathecal iopamidol use, especially w/ high cefazolin doses and/or concomitant renal impairment; consider holding cefazolin at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• cefepime
Isovue (iopamidol)

+

cefepime

1 interaction

Monitor/Modify Tx

iopamidol + cefepime

caution advised if intrathecal iopamidol use, especially w/ high cefepime doses and/or concomitant renal impairment; consider holding cefepime at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• cefiderocol
Isovue (iopamidol)

+

cefiderocol

1 interaction

Monitor/Modify Tx

iopamidol + cefiderocol

caution advised if intrathecal iopamidol use, especially w/ high cefiderocol doses and/or concomitant renal impairment; consider holding cefiderocol at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• ceftaroline
Isovue (iopamidol)

+

ceftaroline

1 interaction

Monitor/Modify Tx

iopamidol + ceftaroline

caution advised if intrathecal iopamidol use, especially w/ high ceftaroline doses and/or concomitant renal impairment; consider holding ceftaroline at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• ceftazidime
Isovue (iopamidol)

+

ceftazidime

1 interaction

Monitor/Modify Tx

iopamidol + ceftazidime

caution advised if intrathecal iopamidol use, especially w/ high ceftazidime doses and/or concomitant renal impairment; consider holding ceftazidime at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• ceftobiprole
Isovue (iopamidol)

+

ceftobiprole

1 interaction

Monitor/Modify Tx

iopamidol + ceftobiprole

caution advised if intrathecal iopamidol use; consider holding ceftobiprole at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• celecoxib
Isovue (iopamidol)

+

celecoxib

1 interaction

Monitor/Modify Tx

iopamidol + celecoxib

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective celecoxib dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• chlorambucil
Isovue (iopamidol)

+

chlorambucil

1 interaction

Monitor/Modify Tx

iopamidol + chlorambucil

caution advised if intrathecal iopamidol use; consider holding chlorambucil at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• chloroquine
Isovue (iopamidol)

+

chloroquine

1 interaction

Monitor/Modify Tx

iopamidol + chloroquine

caution advised if intrathecal iopamidol use; consider holding chloroquine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• chlorothiazide
Isovue (iopamidol)

+

chlorothiazide

1 interaction

Monitor/Modify Tx

iopamidol + chlorothiazide

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• chlorpromazine
Isovue (iopamidol)

+

chlorpromazine

1 interaction

Monitor/Modify Tx

iopamidol + chlorpromazine

caution advised if intrathecal iopamidol use; consider holding chlorpromazine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• chlorthalidone
Isovue (iopamidol)

+

chlorthalidone

1 interaction

Monitor/Modify Tx

iopamidol + chlorthalidone

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• chorionic gonadotropin
Isovue (iopamidol)

+

chorionic gonadotropin

1 interaction

Monitor/Modify Tx

iopamidol + chorionic gonadotropin

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• ciltacabtagene autoleucel
Isovue (iopamidol)

+

ciltacabtagene autoleucel

1 interaction

Monitor/Modify Tx

iopamidol + ciltacabtagene autoleucel

caution advised if intrathecal iopamidol use: combo may incr. risk of seizures (additive effects)

• ciprofloxacin
Isovue (iopamidol)

+

ciprofloxacin

1 interaction

Monitor/Modify Tx

iopamidol + ciprofloxacin

caution advised if intrathecal iopamidol use; consider holding ciprofloxacin at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• cisatracurium
Isovue (iopamidol)

+

cisatracurium

1 interaction

Monitor/Modify Tx

iopamidol + cisatracurium

caution advised if intrathecal iopamidol use; consider holding cisatracurium at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• cisplatin
Isovue (iopamidol)

+

cisplatin

1 interaction

Monitor/Modify Tx

iopamidol + cisplatin

if IV iopamidol use, monitor CBC, renal fxn, ototoxicity: combo may incr. cisplatin levels, risk of serious infection, myelosuppression, nephrotoxicity, auditory, vestibular, other adverse effects (additive effects)

• citalopram
Isovue (iopamidol)

+

citalopram

1 interaction

Monitor/Modify Tx

iopamidol + citalopram

caution advised if intrathecal iopamidol use; consider holding citalopram at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• clindamycin
Isovue (iopamidol)

+

clindamycin

1 interaction

Monitor/Modify Tx

iopamidol + clindamycin

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• clomipramine
Isovue (iopamidol)

+

clomipramine

1 interaction

Monitor/Modify Tx

iopamidol + clomipramine

caution advised if intrathecal iopamidol use; consider holding clomipramine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• clozapine
Isovue (iopamidol)

+

clozapine

1 interaction

Monitor/Modify Tx

iopamidol + clozapine

if IV iopamidol use, monitor thrombosis s/sx; caution advised if intrathecal iopamidol use; consider holding clozapine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of thromboembolism, seizures (additive effects)

• coagulation factor IX
Isovue (iopamidol)

+

coagulation factor IX

1 interaction

Monitor/Modify Tx

iopamidol + coagulation factor IX

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• coagulation factor VIIa
Isovue (iopamidol)

+

coagulation factor VIIa

1 interaction

Monitor/Modify Tx

iopamidol + coagulation factor VIIa

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• coagulation factor XIII A-subunit
Isovue (iopamidol)

+

coagulation factor XIII A-subunit

1 interaction

Monitor/Modify Tx

iopamidol + coagulation factor XIII A-subunit

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• cocaine
Isovue (iopamidol)

+

cocaine

1 interaction

Monitor/Modify Tx

iopamidol + cocaine

caution advised if intrathecal iopamidol use; consider holding cocaine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• codeine
Isovue (iopamidol)

+

codeine

1 interaction

Monitor/Modify Tx

iopamidol + codeine

caution advised if intrathecal iopamidol use; consider holding codeine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• colistimethate
Isovue (iopamidol)

+

colistimethate

1 interaction

Monitor/Modify Tx

iopamidol + colistimethate

if IV iopamidol use, monitor renal fxn: combo may incr. colistimethate levels, risk of nephrotoxicity, other adverse effects (additive effects)

• concizumab
Isovue (iopamidol)

+

concizumab

1 interaction

Monitor/Modify Tx

iopamidol + concizumab

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• cortisone
Isovue (iopamidol)

+

cortisone

1 interaction

Monitor/Modify Tx

iopamidol + cortisone

caution advised if intrathecal iopamidol use; consider holding cortisone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• creatine
Isovue (iopamidol)

+

creatine

1 interaction

Monitor/Modify Tx

iopamidol + creatine

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• cyclobenzaprine
Isovue (iopamidol)

+

cyclobenzaprine

1 interaction

Monitor/Modify Tx

iopamidol + cyclobenzaprine

caution advised if intrathecal iopamidol use; consider holding cyclobenzaprine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• cyclophosphamide
Isovue (iopamidol)

+

cyclophosphamide

1 interaction

Monitor/Modify Tx

iopamidol + cyclophosphamide

if IV iopamidol use, monitor CBC, renal, cardiac fxn: combo may incr. cyclophosphamide levels, risk of serious infection, myelosuppression, nephrotoxicity, cardiotoxicity, other adverse effects (additive effects)

• cyclosporine
Isovue (iopamidol)

+

cyclosporine

1 interaction

Monitor/Modify Tx

iopamidol + cyclosporine

if IV iopamidol use, monitor renal fxn; caution advised if intrathecal iopamidol use; consider holding cyclosporine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of nephrotoxicity, seizures (additive effects)

• cytomegalovirus immune globulin
Isovue (iopamidol)

+

cytomegalovirus immune globulin

1 interaction

Monitor/Modify Tx

iopamidol + cytomegalovirus immune globulin

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest cytomegalovirus immune globulin concentration and infusion rate possible: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• dalfampridine
Isovue (iopamidol)

+

dalfampridine

1 interaction

Monitor/Modify Tx

iopamidol + dalfampridine

caution advised if intrathecal iopamidol use; consider holding dalfampridine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• danazol
Isovue (iopamidol)

+

danazol

1 interaction

Monitor/Modify Tx

iopamidol + danazol

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• darbepoetin alfa
Isovue (iopamidol)

+

darbepoetin alfa

1 interaction

Monitor/Modify Tx

iopamidol + darbepoetin alfa

if IV iopamidol use, monitor thrombosis s/sx; caution advised if intrathecal iopamidol use; consider holding darbepoetin alfa at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of thromboembolism, seizures (additive effects)

• darolutamide
Isovue (iopamidol)

+

darolutamide

1 interaction

Monitor/Modify Tx

iopamidol + darolutamide

caution advised if intrathecal iopamidol use; consider holding darolutamide at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• deferasirox
Isovue (iopamidol)

+

deferasirox

1 interaction

Monitor/Modify Tx

iopamidol + deferasirox

if IV iopamidol use, monitor CBC, renal fxn, ototoxicity: combo may incr. deferasirox levels, risk of myelosuppression, nephrotoxicity, auditory, vestibular, other adverse effects (additive effects)

• deferoxamine
Isovue (iopamidol)

+

deferoxamine

1 interaction

Monitor/Modify Tx

iopamidol + deferoxamine

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• deflazacort
Isovue (iopamidol)

+

deflazacort

1 interaction

Monitor/Modify Tx

iopamidol + deflazacort

if IV iopamidol use, monitor thrombosis s/sx; caution advised if intrathecal iopamidol use; consider holding deflazacort at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of thromboembolism, seizures (additive effects)

• delafloxacin
Isovue (iopamidol)

+

delafloxacin

1 interaction

Monitor/Modify Tx

iopamidol + delafloxacin

caution advised if intrathecal iopamidol use; consider holding delafloxacin at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• desipramine
Isovue (iopamidol)

+

desipramine

1 interaction

Monitor/Modify Tx

iopamidol + desipramine

caution advised if intrathecal iopamidol use; consider holding desipramine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• desogestrel (contraceptive)
Isovue (iopamidol)

+

desogestrel (contraceptive)

1 interaction

Monitor/Modify Tx

iopamidol + desogestrel (contraceptive)

if IV iopamidol use, monitor thrombosis s/sx, especially w/ concomitant estrogen use: combo may incr. risk of thromboembolism (additive effects)

• desvenlafaxine
Isovue (iopamidol)

+

desvenlafaxine

1 interaction

Monitor/Modify Tx

iopamidol + desvenlafaxine

caution advised if intrathecal iopamidol use; consider holding desvenlafaxine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• deuruxolitinib
Isovue (iopamidol)

+

deuruxolitinib

1 interaction

Monitor/Modify Tx

iopamidol + deuruxolitinib

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• dexmethylphenidate
Isovue (iopamidol)

+

dexmethylphenidate

1 interaction

Monitor/Modify Tx

iopamidol + dexmethylphenidate

caution advised if intrathecal iopamidol use; consider holding dexmethylphenidate at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• dextroamphetamine
Isovue (iopamidol)

+

dextroamphetamine

1 interaction

Monitor/Modify Tx

iopamidol + dextroamphetamine

caution advised if intrathecal iopamidol use; consider holding dextroamphetamine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• diclofenac
Isovue (iopamidol)

+

diclofenac

1 interaction

Monitor/Modify Tx

iopamidol + diclofenac

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective diclofenac dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• diclofenac topical
Isovue (iopamidol)

+

diclofenac topical

1 interaction

Monitor/Modify Tx

iopamidol + diclofenac topical

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective diclofenac dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• dicloxacillin
Isovue (iopamidol)

+

dicloxacillin

1 interaction

Monitor/Modify Tx

iopamidol + dicloxacillin

caution advised if intrathecal iopamidol use, especially w/ high dicloxacillin doses or concomitant renal impairment; consider holding dicloxacillin at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• dienogest (contraceptive)
Isovue (iopamidol)

+

dienogest (contraceptive)

1 interaction

Monitor/Modify Tx

iopamidol + dienogest (contraceptive)

if IV iopamidol use, monitor thrombosis s/sx, especially w/ concomitant estrogen use: combo may incr. risk of thromboembolism (additive effects)

• diethylpropion
Isovue (iopamidol)

+

diethylpropion

1 interaction

Monitor/Modify Tx

iopamidol + diethylpropion

caution advised if intrathecal iopamidol use; consider holding diethylpropion at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• diflunisal
Isovue (iopamidol)

+

diflunisal

1 interaction

Monitor/Modify Tx

iopamidol + diflunisal

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective diflunisal dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• dihydrocodeine
Isovue (iopamidol)

+

dihydrocodeine

1 interaction

Monitor/Modify Tx

iopamidol + dihydrocodeine

caution advised if intrathecal iopamidol use; consider holding dihydrocodeine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• donepezil
Isovue (iopamidol)

+

donepezil

1 interaction

Monitor/Modify Tx

iopamidol + donepezil

caution advised if intrathecal iopamidol use; consider holding donepezil at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• doxepin
Isovue (iopamidol)

+

doxepin

1 interaction

Monitor/Modify Tx

iopamidol + doxepin

caution advised if intrathecal iopamidol use; consider holding doxepin at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• dronabinol
Isovue (iopamidol)

+

dronabinol

1 interaction

Monitor/Modify Tx

iopamidol + dronabinol

caution advised if intrathecal iopamidol use; consider holding dronabinol at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• drospirenone (contraceptive)
Isovue (iopamidol)

+

drospirenone (contraceptive)

1 interaction

Monitor/Modify Tx

iopamidol + drospirenone (contraceptive)

if IV iopamidol use, monitor thrombosis s/sx, especially w/ concomitant estrogen use: combo may incr. risk of thromboembolism (additive effects)

• drospirenone (hormone replacement)
Isovue (iopamidol)

+

drospirenone (hormone replacement)

1 interaction

Monitor/Modify Tx

iopamidol + drospirenone (hormone replacement)

if IV iopamidol use, monitor thrombosis s/sx, especially w/ concomitant estrogen use: combo may incr. risk of thromboembolism (additive effects)

• duloxetine
Isovue (iopamidol)

+

duloxetine

1 interaction

Monitor/Modify Tx

iopamidol + duloxetine

caution advised if intrathecal iopamidol use; consider holding duloxetine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• elinzanetant
Isovue (iopamidol)

+

elinzanetant

1 interaction

Monitor/Modify Tx

iopamidol + elinzanetant

caution advised if intrathecal iopamidol use; consider holding elinzanetant at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• elivaldogene autotemcel
Isovue (iopamidol)

+

elivaldogene autotemcel

1 interaction

Monitor/Modify Tx

iopamidol + elivaldogene autotemcel

caution advised if intrathecal iopamidol use: combo may incr. risk of seizures (additive effects)

• eltrombopag
Isovue (iopamidol)

+

eltrombopag

1 interaction

Monitor/Modify Tx

iopamidol + eltrombopag

if IV iopamidol use, monitor platelets, thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• enalapril
Isovue (iopamidol)

+

enalapril

1 interaction

Monitor/Modify Tx

iopamidol + enalapril

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• enalaprilat
Isovue (iopamidol)

+

enalaprilat

1 interaction

Monitor/Modify Tx

iopamidol + enalaprilat

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• enzalutamide
Isovue (iopamidol)

+

enzalutamide

1 interaction

Monitor/Modify Tx

iopamidol + enzalutamide

caution advised if intrathecal iopamidol use; consider holding enzalutamide at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• ephedra
Isovue (iopamidol)

+

ephedra

1 interaction

Monitor/Modify Tx

iopamidol + ephedra

caution advised if intrathecal iopamidol use; consider holding ephedra at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• epirubicin
Isovue (iopamidol)

+

epirubicin

1 interaction

Monitor/Modify Tx

iopamidol + epirubicin

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• epoetin alfa
Isovue (iopamidol)

+

epoetin alfa

1 interaction

Monitor/Modify Tx

iopamidol + epoetin alfa

if IV iopamidol use, monitor thrombosis s/sx; caution advised if intrathecal iopamidol use; consider holding epoetin alfa at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of thromboembolism, seizures (additive effects)

• ertapenem
Isovue (iopamidol)

+

ertapenem

1 interaction

Monitor/Modify Tx

iopamidol + ertapenem

caution advised if intrathecal iopamidol use; consider holding ertapenem at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• escitalopram
Isovue (iopamidol)

+

escitalopram

1 interaction

Monitor/Modify Tx

iopamidol + escitalopram

caution advised if intrathecal iopamidol use; consider holding escitalopram at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• estetrol (contraceptive)
Isovue (iopamidol)

+

estetrol (contraceptive)

1 interaction

Monitor/Modify Tx

iopamidol + estetrol (contraceptive)

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• estradiol (contraceptive)
Isovue (iopamidol)

+

estradiol (contraceptive)

1 interaction

Monitor/Modify Tx

iopamidol + estradiol (contraceptive)

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• estradiol (hormone replacement)
Isovue (iopamidol)

+

estradiol (hormone replacement)

1 interaction

Monitor/Modify Tx

iopamidol + estradiol (hormone replacement)

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• estrogens, conjugated (hormone replacement)
Isovue (iopamidol)

+

estrogens, conjugated (hormone replacement)

1 interaction

Monitor/Modify Tx

iopamidol + estrogens, conjugated (hormone replacement)

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• estrogens, esterified (hormone replacement)
Isovue (iopamidol)

+

estrogens, esterified (hormone replacement)

1 interaction

Monitor/Modify Tx

iopamidol + estrogens, esterified (hormone replacement)

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• ethacrynic acid
Isovue (iopamidol)

+

ethacrynic acid

1 interaction

Monitor/Modify Tx

iopamidol + ethacrynic acid

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• ethinyl estradiol (contraceptive)
Isovue (iopamidol)

+

ethinyl estradiol (contraceptive)

1 interaction

Monitor/Modify Tx

iopamidol + ethinyl estradiol (contraceptive)

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• ethinyl estradiol (hormone replacement)
Isovue (iopamidol)

+

ethinyl estradiol (hormone replacement)

1 interaction

Monitor/Modify Tx

iopamidol + ethinyl estradiol (hormone replacement)

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• ethynodiol (contraceptive)
Isovue (iopamidol)

+

ethynodiol (contraceptive)

1 interaction

Monitor/Modify Tx

iopamidol + ethynodiol (contraceptive)

if IV iopamidol use, monitor thrombosis s/sx, especially w/ concomitant estrogen use: combo may incr. risk of thromboembolism (additive effects)

• etodolac
Isovue (iopamidol)

+

etodolac

1 interaction

Monitor/Modify Tx

iopamidol + etodolac

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective etodolac dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• etonogestrel (contraceptive)
Isovue (iopamidol)

+

etonogestrel (contraceptive)

1 interaction

Monitor/Modify Tx

iopamidol + etonogestrel (contraceptive)

if IV iopamidol use, monitor thrombosis s/sx, especially w/ concomitant estrogen use: combo may incr. risk of thromboembolism (additive effects)

• everolimus
Isovue (iopamidol)

+

everolimus

1 interaction

Monitor/Modify Tx

iopamidol + everolimus

if IV iopamidol use, monitor renal fxn, thrombosis s/sx, especially if immunosuppressant use: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• factor XIII concentrate
Isovue (iopamidol)

+

factor XIII concentrate

1 interaction

Monitor/Modify Tx

iopamidol + factor XIII concentrate

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• faricimab
Isovue (iopamidol)

+

faricimab

1 interaction

Monitor/Modify Tx

iopamidol + faricimab

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• fedratinib
Isovue (iopamidol)

+

fedratinib

1 interaction

Monitor/Modify Tx

iopamidol + fedratinib

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• fenofibrate
Isovue (iopamidol)

+

fenofibrate

1 interaction

Monitor/Modify Tx

iopamidol + fenofibrate

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• fenofibric acid
Isovue (iopamidol)

+

fenofibric acid

1 interaction

Monitor/Modify Tx

iopamidol + fenofibric acid

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• fenoprofen
Isovue (iopamidol)

+

fenoprofen

1 interaction

Monitor/Modify Tx

iopamidol + fenoprofen

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective fenoprofen dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• fentanyl
Isovue (iopamidol)

+

fentanyl

1 interaction

Monitor/Modify Tx

iopamidol + fentanyl

caution advised if intrathecal iopamidol use; consider holding fentanyl at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• fitusiran
Isovue (iopamidol)

+

fitusiran

1 interaction

Monitor/Modify Tx

iopamidol + fitusiran

if IV iopamidol use, monitor antithrombin activity level, thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• flucytosine
Isovue (iopamidol)

+

flucytosine

1 interaction

Monitor/Modify Tx

iopamidol + flucytosine

if IV iopamidol use, monitor CBC, renal fxn, flucytosine levels: combo may incr. flucytosine levels, risk of myelosuppression, nephrotoxicity, other adverse effects (additive effects)

• fluoxetine
Isovue (iopamidol)

+

fluoxetine

1 interaction

Monitor/Modify Tx

iopamidol + fluoxetine

caution advised if intrathecal iopamidol use; consider holding fluoxetine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• fluphenazine
Isovue (iopamidol)

+

fluphenazine

1 interaction

Monitor/Modify Tx

iopamidol + fluphenazine

caution advised if intrathecal iopamidol use; consider holding fluphenazine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• flurbiprofen
Isovue (iopamidol)

+

flurbiprofen

1 interaction

Monitor/Modify Tx

iopamidol + flurbiprofen

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective flurbiprofen dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• fluvoxamine
Isovue (iopamidol)

+

fluvoxamine

1 interaction

Monitor/Modify Tx

iopamidol + fluvoxamine

caution advised if intrathecal iopamidol use; consider holding fluvoxamine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• follitropin
Isovue (iopamidol)

+

follitropin

1 interaction

Monitor/Modify Tx

iopamidol + follitropin

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• fosinopril
Isovue (iopamidol)

+

fosinopril

1 interaction

Monitor/Modify Tx

iopamidol + fosinopril

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• fruquintinib
Isovue (iopamidol)

+

fruquintinib

1 interaction

Monitor/Modify Tx

iopamidol + fruquintinib

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• furosemide
Isovue (iopamidol)

+

furosemide

1 interaction

Monitor/Modify Tx

iopamidol + furosemide

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• galantamine
Isovue (iopamidol)

+

galantamine

1 interaction

Monitor/Modify Tx

iopamidol + galantamine

caution advised if intrathecal iopamidol use; consider holding galantamine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• ginkgo
Isovue (iopamidol)

+

ginkgo

1 interaction

Monitor/Modify Tx

iopamidol + ginkgo

if intrathecal iopamidol use, avoid consumption of ginkgo seeds; otherwise, caution advised if intrathecal iopamidol use; consider holding ginkgo at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• goserelin
Isovue (iopamidol)

+

goserelin

1 interaction

Monitor/Modify Tx

iopamidol + goserelin

caution advised if intrathecal iopamidol use; consider holding goserelin at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• haloperidol
Isovue (iopamidol)

+

haloperidol

1 interaction

Monitor/Modify Tx

iopamidol + haloperidol

caution advised if intrathecal iopamidol use; consider holding haloperidol at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• hepatitis B immune globulin
Isovue (iopamidol)

+

hepatitis B immune globulin

1 interaction

Monitor/Modify Tx

iopamidol + hepatitis B immune globulin

if IV iopamidol use, monitor thrombosis s/sx; use lowest hepatitis B immune globulin infusion rate possible: combo may incr. risk of thromboembolism (additive effects)

• histrelin
Isovue (iopamidol)

+

histrelin

1 interaction

Monitor/Modify Tx

iopamidol + histrelin

caution advised if intrathecal iopamidol use; consider holding histrelin at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• hydrochlorothiazide
Isovue (iopamidol)

+

hydrochlorothiazide

1 interaction

Monitor/Modify Tx

iopamidol + hydrochlorothiazide

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• hydrocodone
Isovue (iopamidol)

+

hydrocodone

1 interaction

Monitor/Modify Tx

iopamidol + hydrocodone

caution advised if intrathecal iopamidol use; consider holding hydrocodone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• hydromorphone
Isovue (iopamidol)

+

hydromorphone

1 interaction

Monitor/Modify Tx

iopamidol + hydromorphone

caution advised if intrathecal iopamidol use; consider holding hydromorphone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• hydroxocobalamin IV
Isovue (iopamidol)

+

hydroxocobalamin IV

1 interaction

Monitor/Modify Tx

iopamidol + hydroxocobalamin IV

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• hydroxychloroquine
Isovue (iopamidol)

+

hydroxychloroquine

1 interaction

Monitor/Modify Tx

iopamidol + hydroxychloroquine

caution advised if intrathecal iopamidol use; consider holding hydroxychloroquine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• ibuprofen
Isovue (iopamidol)

+

ibuprofen

1 interaction

Monitor/Modify Tx

iopamidol + ibuprofen

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective ibuprofen dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• ibuprofen lysine
Isovue (iopamidol)

+

ibuprofen lysine

1 interaction

Monitor/Modify Tx

iopamidol + ibuprofen lysine

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• idecabtagene vicleucel
Isovue (iopamidol)

+

idecabtagene vicleucel

1 interaction

Monitor/Modify Tx

iopamidol + idecabtagene vicleucel

caution advised if intrathecal iopamidol use: combo may incr. risk of seizures (additive effects)

• ifosfamide
Isovue (iopamidol)

+

ifosfamide

1 interaction

Monitor/Modify Tx

iopamidol + ifosfamide

if IV iopamidol use, monitor CBC, renal, cardiac fxn; caution advised if intrathecal iopamidol use; consider holding ifosfamide at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. ifosfamide levels, risk of myelosuppression, serious infection, encephalopathy, nephrotoxicity, cardiotoxicity, seizures, other adverse effects (additive effects)

• iloperidone
Isovue (iopamidol)

+

iloperidone

1 interaction

Monitor/Modify Tx

iopamidol + iloperidone

caution advised if intrathecal iopamidol use; consider holding iloperidone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• imipenem
Isovue (iopamidol)

+

imipenem

1 interaction

Monitor/Modify Tx

iopamidol + imipenem

caution advised if intrathecal iopamidol use; consider holding imipenem at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• imipramine
Isovue (iopamidol)

+

imipramine

1 interaction

Monitor/Modify Tx

iopamidol + imipramine

caution advised if intrathecal iopamidol use; consider holding imipramine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• immune globulin
Isovue (iopamidol)

+

immune globulin

1 interaction

Monitor/Modify Tx

iopamidol + immune globulin

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest immune globulin dose, concentration and infusion rate possible: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• indapamide
Isovue (iopamidol)

+

indapamide

1 interaction

Monitor/Modify Tx

iopamidol + indapamide

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• indomethacin
Isovue (iopamidol)

+

indomethacin

1 interaction

Monitor/Modify Tx

iopamidol + indomethacin

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective indomethacin dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• interferon beta 1a
Isovue (iopamidol)

+

interferon beta 1a

1 interaction

Monitor/Modify Tx

iopamidol + interferon beta 1a

caution advised if intrathecal iopamidol use; consider holding interferon beta 1a at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• interferon beta 1b
Isovue (iopamidol)

+

interferon beta 1b

1 interaction

Monitor/Modify Tx

iopamidol + interferon beta 1b

caution advised if intrathecal iopamidol use; consider holding interferon beta 1b at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• irbesartan
Isovue (iopamidol)

+

irbesartan

1 interaction

Monitor/Modify Tx

iopamidol + irbesartan

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• isocarboxazid
Isovue (iopamidol)

+

isocarboxazid

1 interaction

Monitor/Modify Tx

iopamidol + isocarboxazid

caution advised if intrathecal iopamidol use; consider holding isocarboxazid at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• isoniazid
Isovue (iopamidol)

+

isoniazid

1 interaction

Monitor/Modify Tx

iopamidol + isoniazid

caution advised if intrathecal iopamidol use; consider holding isoniazid at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• ketamine
Isovue (iopamidol)

+

ketamine

1 interaction

Monitor/Modify Tx

iopamidol + ketamine

caution advised if intrathecal iopamidol use; consider holding ketamine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• ketoprofen
Isovue (iopamidol)

+

ketoprofen

1 interaction

Monitor/Modify Tx

iopamidol + ketoprofen

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective ketoprofen dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• ketorolac
Isovue (iopamidol)

+

ketorolac

1 interaction

Monitor/Modify Tx

iopamidol + ketorolac

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective ketorolac dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• kratom
Isovue (iopamidol)

+

kratom

1 interaction

Monitor/Modify Tx

iopamidol + kratom

caution advised if intrathecal iopamidol use; consider holding kratom at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• lazertinib
Isovue (iopamidol)

+

lazertinib

1 interaction

Monitor/Modify Tx

iopamidol + lazertinib

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• lenalidomide
Isovue (iopamidol)

+

lenalidomide

1 interaction

Monitor/Modify Tx

iopamidol + lenalidomide

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• lenvatinib
Isovue (iopamidol)

+

lenvatinib

1 interaction

Monitor/Modify Tx

iopamidol + lenvatinib

if IV iopamidol use, monitor renal fxn, thrombosis s/sx: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• leuprolide
Isovue (iopamidol)

+

leuprolide

1 interaction

Monitor/Modify Tx

iopamidol + leuprolide

caution advised if intrathecal iopamidol use; consider holding leuprolide at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• levocarnitine
Isovue (iopamidol)

+

levocarnitine

1 interaction

Monitor/Modify Tx

iopamidol + levocarnitine

caution advised if intrathecal iopamidol use; consider holding levocarnitine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• levofloxacin
Isovue (iopamidol)

+

levofloxacin

1 interaction

Monitor/Modify Tx

iopamidol + levofloxacin

caution advised if intrathecal iopamidol use; consider holding levofloxacin at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• levomilnacipran
Isovue (iopamidol)

+

levomilnacipran

1 interaction

Monitor/Modify Tx

iopamidol + levomilnacipran

caution advised if intrathecal iopamidol use; consider holding levomilnacipran at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• levonorgestrel (contraceptive)
Isovue (iopamidol)

+

levonorgestrel (contraceptive)

1 interaction

Monitor/Modify Tx

iopamidol + levonorgestrel (contraceptive)

if IV iopamidol use, monitor thrombosis s/sx, especially w/ concomitant estrogen use: combo may incr. risk of thromboembolism (additive effects)

• levonorgestrel (hormone replacement)
Isovue (iopamidol)

+

levonorgestrel (hormone replacement)

1 interaction

Monitor/Modify Tx

iopamidol + levonorgestrel (hormone replacement)

if IV iopamidol use, monitor thrombosis s/sx, especially w/ concomitant estrogen use: combo may incr. risk of thromboembolism (additive effects)

• levorphanol
Isovue (iopamidol)

+

levorphanol

1 interaction

Monitor/Modify Tx

iopamidol + levorphanol

caution advised if intrathecal iopamidol use; consider holding levorphanol at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• lidocaine
Isovue (iopamidol)

+

lidocaine

1 interaction

Monitor/Modify Tx

iopamidol + lidocaine

caution advised if intrathecal iopamidol use; consider holding lidocaine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• lidocaine topical
Isovue (iopamidol)

+

lidocaine topical

1 interaction

Monitor/Modify Tx

iopamidol + lidocaine topical

caution advised if intrathecal iopamidol use; consider holding lidocaine topical at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• lifileucel
Isovue (iopamidol)

+

lifileucel

1 interaction

Monitor/Modify Tx

iopamidol + lifileucel

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• linezolid
Isovue (iopamidol)

+

linezolid

1 interaction

Monitor/Modify Tx

iopamidol + linezolid

caution advised if intrathecal iopamidol use; consider holding linezolid at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• lisdexamfetamine
Isovue (iopamidol)

+

lisdexamfetamine

1 interaction

Monitor/Modify Tx

iopamidol + lisdexamfetamine

caution advised if intrathecal iopamidol use; consider holding lisdexamfetamine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• lisinopril
Isovue (iopamidol)

+

lisinopril

1 interaction

Monitor/Modify Tx

iopamidol + lisinopril

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• lisocabtagene maraleucel
Isovue (iopamidol)

+

lisocabtagene maraleucel

1 interaction

Monitor/Modify Tx

iopamidol + lisocabtagene maraleucel

caution advised if intrathecal iopamidol use: combo may incr. risk of seizures (additive effects)

• lithium
Isovue (iopamidol)

+

lithium

1 interaction

Monitor/Modify Tx

iopamidol + lithium

if IV iopamidol use, monitor lithium levels, renal fxn; caution advised if intrathecal iopamidol use; consider holding lithium at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. lithium levels, risk of nephrotoxicity, seizures, other adverse effects (additive effects)

• lorlatinib
Isovue (iopamidol)

+

lorlatinib

1 interaction

Monitor/Modify Tx

iopamidol + lorlatinib

caution advised if intrathecal iopamidol use; consider holding lorlatinib at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• losartan
Isovue (iopamidol)

+

losartan

1 interaction

Monitor/Modify Tx

iopamidol + losartan

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• loxapine
Isovue (iopamidol)

+

loxapine

1 interaction

Monitor/Modify Tx

iopamidol + loxapine

caution advised if intrathecal iopamidol use; consider holding loxapine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• lumateperone
Isovue (iopamidol)

+

lumateperone

1 interaction

Monitor/Modify Tx

iopamidol + lumateperone

caution advised if intrathecal iopamidol use; consider holding lumateperone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• lurasidone
Isovue (iopamidol)

+

lurasidone

1 interaction

Monitor/Modify Tx

iopamidol + lurasidone

caution advised if intrathecal iopamidol use; consider holding lurasidone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• luspatercept
Isovue (iopamidol)

+

luspatercept

1 interaction

Monitor/Modify Tx

iopamidol + luspatercept

if beta thalassemia use, monitor thrombosis s/sx w/ IV iopamidol use: combo may incr. risk of thromboembolism (additive effects)

• lusutrombopag
Isovue (iopamidol)

+

lusutrombopag

1 interaction

Monitor/Modify Tx

iopamidol + lusutrombopag

if IV iopamidol use, monitor platelets, thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• lutetium Lu 177 vipivotide tetraxetan
Isovue (iopamidol)

+

lutetium Lu 177 vipivotide tetraxetan

1 interaction

Monitor/Modify Tx

iopamidol + lutetium Lu 177 vipivotide tetraxetan

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• magnesium citrate
Isovue (iopamidol)

+

magnesium citrate

1 interaction

Monitor/Modify Tx

iopamidol + magnesium citrate

if IV iopamidol use, monitor renal fxn, especially if magnesium citrate bowel prep use; caution advised if intrathecal iopamidol use, especially if magnesium citrate bowel prep use; consider holding magnesium citrate at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of nephrotoxicity, seizures (additive effects)

• magnesium salicylate
Isovue (iopamidol)

+

magnesium salicylate

1 interaction

Monitor/Modify Tx

iopamidol + magnesium salicylate

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• meclofenamate
Isovue (iopamidol)

+

meclofenamate

1 interaction

Monitor/Modify Tx

iopamidol + meclofenamate

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective meclofenamate dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• medroxyprogesterone (contraceptive)
Isovue (iopamidol)

+

medroxyprogesterone (contraceptive)

1 interaction

Monitor/Modify Tx

iopamidol + medroxyprogesterone (contraceptive)

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• medroxyprogesterone (hormone replacement)
Isovue (iopamidol)

+

medroxyprogesterone (hormone replacement)

1 interaction

Monitor/Modify Tx

iopamidol + medroxyprogesterone (hormone replacement)

if IV iopamidol use, monitor thrombosis s/sx, especially w/ concomitant estrogen use: combo may incr. risk of thromboembolism (additive effects)

• mefenamic acid
Isovue (iopamidol)

+

mefenamic acid

1 interaction

Monitor/Modify Tx

iopamidol + mefenamic acid

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective mefenamic acid dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• mefloquine
Isovue (iopamidol)

+

mefloquine

1 interaction

Monitor/Modify Tx

iopamidol + mefloquine

caution advised if intrathecal iopamidol use; consider holding mefloquine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• megestrol
Isovue (iopamidol)

+

megestrol

1 interaction

Monitor/Modify Tx

iopamidol + megestrol

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• melatonin
Isovue (iopamidol)

+

melatonin

1 interaction

Monitor/Modify Tx

iopamidol + melatonin

caution advised if intrathecal iopamidol use; consider holding melatonin at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• meloxicam
Isovue (iopamidol)

+

meloxicam

1 interaction

Monitor/Modify Tx

iopamidol + meloxicam

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective meloxicam dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• menotropins
Isovue (iopamidol)

+

menotropins

1 interaction

Monitor/Modify Tx

iopamidol + menotropins

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• meperidine
Isovue (iopamidol)

+

meperidine

1 interaction

Monitor/Modify Tx

iopamidol + meperidine

caution advised if intrathecal iopamidol use; consider holding meperidine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• meropenem
Isovue (iopamidol)

+

meropenem

1 interaction

Monitor/Modify Tx

iopamidol + meropenem

caution advised if intrathecal iopamidol use; consider holding meropenem at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• mesalamine
Isovue (iopamidol)

+

mesalamine

1 interaction

Monitor/Modify Tx

iopamidol + mesalamine

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• mesalamine rectal
Isovue (iopamidol)

+

mesalamine rectal

1 interaction

Monitor/Modify Tx

iopamidol + mesalamine rectal

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• metformin
Isovue (iopamidol)

+

metformin

1 interaction

Monitor/Modify Tx

iopamidol + metformin

if IV iopamidol use, hold metformin if GFR 30-60 mL/min, hepatic impairment, alcoholism, and/or heart failure; may restart metformin if stable renal fxn 48h after iopamidol use: combo may incr. risk of lactic acidosis (possible additive effects)

• methadone
Isovue (iopamidol)

+

methadone

1 interaction

Monitor/Modify Tx

iopamidol + methadone

caution advised if intrathecal iopamidol use; consider holding methadone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• methamphetamine
Isovue (iopamidol)

+

methamphetamine

1 interaction

Monitor/Modify Tx

iopamidol + methamphetamine

caution advised if intrathecal iopamidol use; consider holding methamphetamine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• methocarbamol
Isovue (iopamidol)

+

methocarbamol

1 interaction

Monitor/Modify Tx

iopamidol + methocarbamol

caution advised if intrathecal iopamidol use; consider holding methocarbamol at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• methotrexate
Isovue (iopamidol)

+

methotrexate

1 interaction

Monitor/Modify Tx

iopamidol + methotrexate

if IV iopamidol use, use alternative or monitor CBC, renal fxn; caution advised if intrathecal iopamidol use; consider holding methotrexate at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of nephrotoxicity, seizures (additive effects)

• methoxy polyethylene glycol-epoetin beta
Isovue (iopamidol)

+

methoxy polyethylene glycol-epoetin beta

1 interaction

Monitor/Modify Tx

iopamidol + methoxy polyethylene glycol-epoetin beta

if IV iopamidol use, monitor thrombosis s/sx; caution advised if intrathecal iopamidol use; consider holding methoxy polyethylene glycol-epoetin beta at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of thromboembolism, seizures (additive effects)

• methylphenidate
Isovue (iopamidol)

+

methylphenidate

1 interaction

Monitor/Modify Tx

iopamidol + methylphenidate

caution advised if intrathecal iopamidol use; consider holding methylphenidate at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• methyltestosterone
Isovue (iopamidol)

+

methyltestosterone

1 interaction

Monitor/Modify Tx

iopamidol + methyltestosterone

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• metoclopramide
Isovue (iopamidol)

+

metoclopramide

1 interaction

Monitor/Modify Tx

iopamidol + metoclopramide

caution advised if intrathecal iopamidol use; consider holding metoclopramide at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• metolazone
Isovue (iopamidol)

+

metolazone

1 interaction

Monitor/Modify Tx

iopamidol + metolazone

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• metronidazole
Isovue (iopamidol)

+

metronidazole

1 interaction

Monitor/Modify Tx

iopamidol + metronidazole

caution advised if intrathecal iopamidol use; consider holding metronidazole at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• mexiletine
Isovue (iopamidol)

+

mexiletine

1 interaction

Monitor/Modify Tx

iopamidol + mexiletine

caution advised if intrathecal iopamidol use; consider holding mexiletine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• milnacipran
Isovue (iopamidol)

+

milnacipran

1 interaction

Monitor/Modify Tx

iopamidol + milnacipran

caution advised if intrathecal iopamidol use; consider holding milnacipran at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• mirtazapine
Isovue (iopamidol)

+

mirtazapine

1 interaction

Monitor/Modify Tx

iopamidol + mirtazapine

caution advised if intrathecal iopamidol use; consider holding mirtazapine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• mitomycin
Isovue (iopamidol)

+

mitomycin

1 interaction

Monitor/Modify Tx

iopamidol + mitomycin

if IV iopamidol use, monitor renal fxn; risk may be lower w/ intravesical mitomycin administration: combo may incr. risk of nephrotoxicity (additive effects)

• moexipril
Isovue (iopamidol)

+

moexipril

1 interaction

Monitor/Modify Tx

iopamidol + moexipril

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• molindone
Isovue (iopamidol)

+

molindone

1 interaction

Monitor/Modify Tx

iopamidol + molindone

caution advised if intrathecal iopamidol use; consider holding molindone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• momelotinib
Isovue (iopamidol)

+

momelotinib

1 interaction

Monitor/Modify Tx

iopamidol + momelotinib

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• morphine
Isovue (iopamidol)

+

morphine

1 interaction

Monitor/Modify Tx

iopamidol + morphine

caution advised if intrathecal iopamidol use; consider holding morphine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• moxifloxacin
Isovue (iopamidol)

+

moxifloxacin

1 interaction

Monitor/Modify Tx

iopamidol + moxifloxacin

caution advised if intrathecal iopamidol use; consider holding moxifloxacin at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• nabumetone
Isovue (iopamidol)

+

nabumetone

1 interaction

Monitor/Modify Tx

iopamidol + nabumetone

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective nabumetone dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• nafarelin nasal
Isovue (iopamidol)

+

nafarelin nasal

1 interaction

Monitor/Modify Tx

iopamidol + nafarelin nasal

caution advised if intrathecal iopamidol use; consider holding nafarelin at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• nafcillin
Isovue (iopamidol)

+

nafcillin

1 interaction

Monitor/Modify Tx

iopamidol + nafcillin

caution advised if intrathecal iopamidol use, especially w/ high nafcillin doses or concomitant renal impairment; consider holding nafcillin at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• nalbuphine
Isovue (iopamidol)

+

nalbuphine

1 interaction

Monitor/Modify Tx

iopamidol + nalbuphine

caution advised if intrathecal iopamidol use; consider holding nalbuphine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• naproxen
Isovue (iopamidol)

+

naproxen

1 interaction

Monitor/Modify Tx

iopamidol + naproxen

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective naproxen dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• necitumumab
Isovue (iopamidol)

+

necitumumab

1 interaction

Monitor/Modify Tx

iopamidol + necitumumab

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• nefazodone
Isovue (iopamidol)

+

nefazodone

1 interaction

Monitor/Modify Tx

iopamidol + nefazodone

caution advised if intrathecal iopamidol use; consider holding nefazodone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• nelarabine
Isovue (iopamidol)

+

nelarabine

1 interaction

Monitor/Modify Tx

iopamidol + nelarabine

caution advised if intrathecal iopamidol use; consider holding nelarabine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• neomycin
Isovue (iopamidol)

+

neomycin

1 interaction

Monitor/Modify Tx

iopamidol + neomycin

if compromised gut wall allows for neomycin absorption, monitor renal fxn, ototoxicity if IV iopamidol use: combo may incr. neomycin levels, risk of nephrotoxicity, auditory, vestibular, other adverse effects (additive effects)

• nintedanib
Isovue (iopamidol)

+

nintedanib

1 interaction

Monitor/Modify Tx

iopamidol + nintedanib

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• norelgestromin (contraceptive)
Isovue (iopamidol)

+

norelgestromin (contraceptive)

1 interaction

Monitor/Modify Tx

iopamidol + norelgestromin (contraceptive)

if IV iopamidol use, monitor thrombosis s/sx, especially w/ concomitant estrogen use: combo may incr. risk of thromboembolism (additive effects)

• norethindrone (contraceptive)
Isovue (iopamidol)

+

norethindrone (contraceptive)

1 interaction

Monitor/Modify Tx

iopamidol + norethindrone (contraceptive)

if IV iopamidol use, monitor thrombosis s/sx, especially w/ concomitant estrogen use: combo may incr. risk of thromboembolism (additive effects)

• norethindrone (hormone replacement)
Isovue (iopamidol)

+

norethindrone (hormone replacement)

1 interaction

Monitor/Modify Tx

iopamidol + norethindrone (hormone replacement)

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• norgestimate (contraceptive)
Isovue (iopamidol)

+

norgestimate (contraceptive)

1 interaction

Monitor/Modify Tx

iopamidol + norgestimate (contraceptive)

if IV iopamidol use, monitor thrombosis s/sx, especially w/ concomitant estrogen use: combo may incr. risk of thromboembolism (additive effects)

• norgestrel (contraceptive)
Isovue (iopamidol)

+

norgestrel (contraceptive)

1 interaction

Monitor/Modify Tx

iopamidol + norgestrel (contraceptive)

if IV iopamidol use, monitor thrombosis s/sx, especially w/ concomitant estrogen use: combo may incr. risk of thromboembolism (additive effects)

• nortriptyline
Isovue (iopamidol)

+

nortriptyline

1 interaction

Monitor/Modify Tx

iopamidol + nortriptyline

caution advised if intrathecal iopamidol use; consider holding nortriptyline at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• nusinersen
Isovue (iopamidol)

+

nusinersen

1 interaction

Monitor/Modify Tx

iopamidol + nusinersen

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• obecabtagene autoleucel
Isovue (iopamidol)

+

obecabtagene autoleucel

1 interaction

Monitor/Modify Tx

iopamidol + obecabtagene autoleucel

caution advised if intrathecal iopamidol use; consider holding obecabtagene autoleucel at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• obinutuzumab
Isovue (iopamidol)

+

obinutuzumab

1 interaction

Monitor/Modify Tx

iopamidol + obinutuzumab

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• ofloxacin
Isovue (iopamidol)

+

ofloxacin

1 interaction

Monitor/Modify Tx

iopamidol + ofloxacin

caution advised if intrathecal iopamidol use; consider holding ofloxacin at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• olanzapine
Isovue (iopamidol)

+

olanzapine

1 interaction

Monitor/Modify Tx

iopamidol + olanzapine

caution advised if intrathecal iopamidol use; consider holding olanzapine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• olaparib
Isovue (iopamidol)

+

olaparib

1 interaction

Monitor/Modify Tx

iopamidol + olaparib

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• oliceridine
Isovue (iopamidol)

+

oliceridine

1 interaction

Monitor/Modify Tx

iopamidol + oliceridine

caution advised if intrathecal iopamidol use; consider holding oliceridine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• olmesartan medoxomil
Isovue (iopamidol)

+

olmesartan medoxomil

1 interaction

Monitor/Modify Tx

iopamidol + olmesartan medoxomil

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• olsalazine
Isovue (iopamidol)

+

olsalazine

1 interaction

Monitor/Modify Tx

iopamidol + olsalazine

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• ospemifene
Isovue (iopamidol)

+

ospemifene

1 interaction

Monitor/Modify Tx

iopamidol + ospemifene

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• oxacillin
Isovue (iopamidol)

+

oxacillin

1 interaction

Monitor/Modify Tx

iopamidol + oxacillin

caution advised if intrathecal iopamidol use, especially w/ high oxacillin doses or concomitant renal impairment; consider holding oxacillin at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• oxaprozin
Isovue (iopamidol)

+

oxaprozin

1 interaction

Monitor/Modify Tx

iopamidol + oxaprozin

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective oxaprozin dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• oxycodone
Isovue (iopamidol)

+

oxycodone

1 interaction

Monitor/Modify Tx

iopamidol + oxycodone

caution advised if intrathecal iopamidol use; consider holding oxycodone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• oxymorphone
Isovue (iopamidol)

+

oxymorphone

1 interaction

Monitor/Modify Tx

iopamidol + oxymorphone

caution advised if intrathecal iopamidol use; consider holding oxymorphone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• pacritinib
Isovue (iopamidol)

+

pacritinib

1 interaction

Monitor/Modify Tx

iopamidol + pacritinib

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• paliperidone
Isovue (iopamidol)

+

paliperidone

1 interaction

Monitor/Modify Tx

iopamidol + paliperidone

caution advised if intrathecal iopamidol use; consider holding paliperidone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• pamidronate
Isovue (iopamidol)

+

pamidronate

1 interaction

Monitor/Modify Tx

iopamidol + pamidronate

if IV iopamidol use, monitor renal fxn: combo may incr. pamidronate levels, risk of nephrotoxicity, other adverse effects (additive effects)

• paromomycin
Isovue (iopamidol)

+

paromomycin

1 interaction

Monitor/Modify Tx

iopamidol + paromomycin

if compromised gut wall allows for paromomycin absorption, monitor renal fxn, ototoxicity if IV iopamidol use: combo may incr. paromomycin levels, risk of nephrotoxicity, auditory, vestibular, other adverse effects (additive effects)

• paroxetine
Isovue (iopamidol)

+

paroxetine

1 interaction

Monitor/Modify Tx

iopamidol + paroxetine

caution advised if intrathecal iopamidol use; consider holding paroxetine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• pazopanib
Isovue (iopamidol)

+

pazopanib

1 interaction

Monitor/Modify Tx

iopamidol + pazopanib

if IV iopamidol use, monitor renal fxn, thrombosis s/sx: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• pegaspargase
Isovue (iopamidol)

+

pegaspargase

1 interaction

Monitor/Modify Tx

iopamidol + pegaspargase

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• peginterferon beta 1a
Isovue (iopamidol)

+

peginterferon beta 1a

1 interaction

Monitor/Modify Tx

iopamidol + peginterferon beta 1a

caution advised if intrathecal iopamidol use; consider holding peginterferon beta 1a at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• pemetrexed
Isovue (iopamidol)

+

pemetrexed

1 interaction

Monitor/Modify Tx

iopamidol + pemetrexed

if IV iopamidol use, monitor CBC, renal fxn: combo may incr. pemetrexed levels, risk of myelosuppression, nephrotoxicity, other adverse effects (additive effects)

• penicillamine
Isovue (iopamidol)

+

penicillamine

1 interaction

Monitor/Modify Tx

iopamidol + penicillamine

if IV iopamidol use, monitor CBC, renal fxn: combo may incr. penicillamine levels, risk of myelosuppression, nephrotoxicity, other adverse effects (additive effects)

• penicillin G
Isovue (iopamidol)

+

penicillin G

1 interaction

Monitor/Modify Tx

iopamidol + penicillin G

caution advised if intrathecal iopamidol use, especially w/ high penicillin G doses or concomitant renal impairment; consider holding penicillin G at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• penicillin V
Isovue (iopamidol)

+

penicillin V

1 interaction

Monitor/Modify Tx

iopamidol + penicillin V

caution advised if intrathecal iopamidol use, especially w/ high penicillin V doses or concomitant renal impairment; consider holding penicillin V at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• pentazocine
Isovue (iopamidol)

+

pentazocine

1 interaction

Monitor/Modify Tx

iopamidol + pentazocine

caution advised if intrathecal iopamidol use; consider holding pentazocine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• pentostatin
Isovue (iopamidol)

+

pentostatin

1 interaction

Monitor/Modify Tx

iopamidol + pentostatin

if IV iopamidol use, monitor CBC, renal fxn: combo may incr. pentostatin levels, risk of serious infection, myelosuppression, nephrotoxicity, other adverse effects (additive effects)

• perindopril
Isovue (iopamidol)

+

perindopril

1 interaction

Monitor/Modify Tx

iopamidol + perindopril

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• perphenazine
Isovue (iopamidol)

+

perphenazine

1 interaction

Monitor/Modify Tx

iopamidol + perphenazine

caution advised if intrathecal iopamidol use; consider holding perphenazine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• phendimetrazine
Isovue (iopamidol)

+

phendimetrazine

1 interaction

Monitor/Modify Tx

iopamidol + phendimetrazine

caution advised if intrathecal iopamidol use; consider holding phendimetrazine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• phenelzine
Isovue (iopamidol)

+

phenelzine

1 interaction

Monitor/Modify Tx

iopamidol + phenelzine

caution advised if intrathecal iopamidol use; consider holding phenelzine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• phentermine
Isovue (iopamidol)

+

phentermine

1 interaction

Monitor/Modify Tx

iopamidol + phentermine

caution advised if intrathecal iopamidol use; consider holding phentermine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• pimozide
Isovue (iopamidol)

+

pimozide

1 interaction

Monitor/Modify Tx

iopamidol + pimozide

caution advised if intrathecal iopamidol use; consider holding pimozide at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• piperacillin
Isovue (iopamidol)

+

piperacillin

1 interaction

Monitor/Modify Tx

iopamidol + piperacillin

caution advised if intrathecal iopamidol use, especially w/ high piperacillin doses or concomitant renal impairment; consider holding piperacillin at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• piroxicam
Isovue (iopamidol)

+

piroxicam

1 interaction

Monitor/Modify Tx

iopamidol + piroxicam

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective piroxicam dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• plazomicin
Isovue (iopamidol)

+

plazomicin

1 interaction

Monitor/Modify Tx

iopamidol + plazomicin

if IV iopamidol use, monitor plazomicin levels, renal fxn, ototoxicity: combo may incr. plazomicin levels, risk of nephrotoxicity, auditory, vestibular, other adverse effects (additive effects)

• polyethylene glycol
Isovue (iopamidol)

+

polyethylene glycol

1 interaction

Monitor/Modify Tx

iopamidol + polyethylene glycol

if IV iopamidol use, monitor renal fxn, especially if polyethylene glycol bowel prep use; caution advised if intrathecal iopamidol use, especially if polyethylene glycol bowel prep use; consider holding polyethylene glycol at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of nephrotoxicity, seizures (additive effects)

• polyethylene glycol/electrolytes
Isovue (iopamidol)

+

polyethylene glycol/ electrolytes

1 interaction

Monitor/Modify Tx

iopamidol + polyethylene glycol/ electrolytes

if IV iopamidol use, monitor renal fxn; caution advised if intrathecal iopamidol use; consider holding polyethylene glycol/electrolytes at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of nephrotoxicity, seizures (additive effects)

• pomalidomide
Isovue (iopamidol)

+

pomalidomide

1 interaction

Monitor/Modify Tx

iopamidol + pomalidomide

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• ponatinib
Isovue (iopamidol)

+

ponatinib

1 interaction

Monitor/Modify Tx

iopamidol + ponatinib

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• porfimer
Isovue (iopamidol)

+

porfimer

1 interaction

Monitor/Modify Tx

iopamidol + porfimer

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• prednisolone
Isovue (iopamidol)

+

prednisolone

1 interaction

Monitor/Modify Tx

iopamidol + prednisolone

caution advised if intrathecal iopamidol use; consider holding prednisolone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• prednisone
Isovue (iopamidol)

+

prednisone

1 interaction

Monitor/Modify Tx

iopamidol + prednisone

caution advised if intrathecal iopamidol use; consider holding prednisone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• procarbazine
Isovue (iopamidol)

+

procarbazine

1 interaction

Monitor/Modify Tx

iopamidol + procarbazine

caution advised if intrathecal iopamidol use; consider holding procarbazine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• prochlorperazine
Isovue (iopamidol)

+

prochlorperazine

1 interaction

Monitor/Modify Tx

iopamidol + prochlorperazine

caution advised if intrathecal iopamidol use; consider holding prochlorperazine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• progesterone (hormone replacement)
Isovue (iopamidol)

+

progesterone (hormone replacement)

1 interaction

Monitor/Modify Tx

iopamidol + progesterone (hormone replacement)

if IV iopamidol use, monitor thrombosis s/sx, especially w/ concomitant estrogen use: combo may incr. risk of thromboembolism (additive effects)

• progesterone vaginal (hormone replacement)
Isovue (iopamidol)

+

progesterone vaginal (hormone replacement)

1 interaction

Monitor/Modify Tx

iopamidol + progesterone vaginal (hormone replacement)

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• promethazine
Isovue (iopamidol)

+

promethazine

1 interaction

Monitor/Modify Tx

iopamidol + promethazine

caution advised if intrathecal iopamidol use; consider holding promethazine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• propofol
Isovue (iopamidol)

+

propofol

1 interaction

Monitor/Modify Tx

iopamidol + propofol

caution advised if intrathecal iopamidol use; consider holding propofol at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• prothrombin complex concentrate (human)
Isovue (iopamidol)

+

prothrombin complex concentrate (human)

1 interaction

Monitor/Modify Tx

iopamidol + prothrombin complex concentrate (human)

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• protriptyline
Isovue (iopamidol)

+

protriptyline

1 interaction

Monitor/Modify Tx

iopamidol + protriptyline

caution advised if intrathecal iopamidol use; consider holding protriptyline at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• pyridostigmine
Isovue (iopamidol)

+

pyridostigmine

1 interaction

Monitor/Modify Tx

iopamidol + pyridostigmine

caution advised if intrathecal iopamidol use; consider holding pyridostigmine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• pyrimethamine
Isovue (iopamidol)

+

pyrimethamine

1 interaction

Monitor/Modify Tx

iopamidol + pyrimethamine

caution advised if intrathecal iopamidol use; consider holding pyrimethamine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• quetiapine
Isovue (iopamidol)

+

quetiapine

1 interaction

Monitor/Modify Tx

iopamidol + quetiapine

caution advised if intrathecal iopamidol use; consider holding quetiapine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• quinapril
Isovue (iopamidol)

+

quinapril

1 interaction

Monitor/Modify Tx

iopamidol + quinapril

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• quinine
Isovue (iopamidol)

+

quinine

1 interaction

Monitor/Modify Tx

iopamidol + quinine

caution advised if intrathecal iopamidol use; consider holding quinine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• raloxifene
Isovue (iopamidol)

+

raloxifene

1 interaction

Monitor/Modify Tx

iopamidol + raloxifene

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• ramipril
Isovue (iopamidol)

+

ramipril

1 interaction

Monitor/Modify Tx

iopamidol + ramipril

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• ramucirumab
Isovue (iopamidol)

+

ramucirumab

1 interaction

Monitor/Modify Tx

iopamidol + ramucirumab

if IV iopamidol use, monitor renal fxn, thrombosis s/sx: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• ranibizumab
Isovue (iopamidol)

+

ranibizumab

1 interaction

Monitor/Modify Tx

iopamidol + ranibizumab

if IV iopamidol use, monitor thrombosis s/sx; risk may be lower if ocular implant use: combo may incr. risk of thromboembolism (additive effects)

• regadenoson
Isovue (iopamidol)

+

regadenoson

1 interaction

Monitor/Modify Tx

iopamidol + regadenoson

caution advised if intrathecal iopamidol use; consider holding regadenoson at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• remifentanil
Isovue (iopamidol)

+

remifentanil

1 interaction

Monitor/Modify Tx

iopamidol + remifentanil

caution advised if intrathecal iopamidol use; consider holding remifentanil at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• Rho(D) immune globulin
Isovue (iopamidol)

+

Rho(D) immune globulin

1 interaction

Monitor/Modify Tx

iopamidol + Rho(D) immune globulin

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest Rho(D) immune globulin infusion rate possible: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• risperidone
Isovue (iopamidol)

+

risperidone

1 interaction

Monitor/Modify Tx

iopamidol + risperidone

caution advised if intrathecal iopamidol use; consider holding risperidone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• ritlecitinib
Isovue (iopamidol)

+

ritlecitinib

1 interaction

Monitor/Modify Tx

iopamidol + ritlecitinib

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• rituximab
Isovue (iopamidol)

+

rituximab

1 interaction

Monitor/Modify Tx

iopamidol + rituximab

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• rivastigmine
Isovue (iopamidol)

+

rivastigmine

1 interaction

Monitor/Modify Tx

iopamidol + rivastigmine

caution advised if intrathecal iopamidol use; consider holding rivastigmine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• romiplostim
Isovue (iopamidol)

+

romiplostim

1 interaction

Monitor/Modify Tx

iopamidol + romiplostim

if IV iopamidol use, monitor platelets, thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• ropeginterferon alfa-2b
Isovue (iopamidol)

+

ropeginterferon alfa-2b

1 interaction

Monitor/Modify Tx

iopamidol + ropeginterferon alfa-2b

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• ruxolitinib
Isovue (iopamidol)

+

ruxolitinib

1 interaction

Monitor/Modify Tx

iopamidol + ruxolitinib

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• ruxolitinib topical
Isovue (iopamidol)

+

ruxolitinib topical

1 interaction

Monitor/Modify Tx

iopamidol + ruxolitinib topical

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• salsalate
Isovue (iopamidol)

+

salsalate

1 interaction

Monitor/Modify Tx

iopamidol + salsalate

if IV iopamidol use, monitor renal fxn, thrombosis s/sx: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• scopolamine
Isovue (iopamidol)

+

scopolamine

1 interaction

Monitor/Modify Tx

iopamidol + scopolamine

caution advised if intrathecal iopamidol use; consider holding scopolamine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• segesterone (contraceptive)
Isovue (iopamidol)

+

segesterone (contraceptive)

1 interaction

Monitor/Modify Tx

iopamidol + segesterone (contraceptive)

if IV iopamidol use, monitor thrombosis s/sx, especially w/ concomitant estrogen use: combo may incr. risk of thromboembolism (additive effects)

• selegiline transdermal
Isovue (iopamidol)

+

selegiline transdermal

1 interaction

Monitor/Modify Tx

iopamidol + selegiline transdermal

caution advised if intrathecal iopamidol use; consider holding selegiline at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• sertraline
Isovue (iopamidol)

+

sertraline

1 interaction

Monitor/Modify Tx

iopamidol + sertraline

caution advised if intrathecal iopamidol use; consider holding sertraline at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• sevoflurane
Isovue (iopamidol)

+

sevoflurane

1 interaction

Monitor/Modify Tx

iopamidol + sevoflurane

caution advised if intrathecal iopamidol use; consider holding sevoflurane at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• sipuleucel-T
Isovue (iopamidol)

+

sipuleucel-T

1 interaction

Monitor/Modify Tx

iopamidol + sipuleucel-T

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• sirolimus
Isovue (iopamidol)

+

sirolimus

1 interaction

Monitor/Modify Tx

iopamidol + sirolimus

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• sitagliptin
Isovue (iopamidol)

+

sitagliptin

1 interaction

Monitor/Modify Tx

iopamidol + sitagliptin

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• sodium picosulfate
Isovue (iopamidol)

+

sodium picosulfate

1 interaction

Monitor/Modify Tx

iopamidol + sodium picosulfate

caution advised if intrathecal iopamidol use; consider holding sodium picosulfate at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• sodium tetradecyl sulfate
Isovue (iopamidol)

+

sodium tetradecyl sulfate

1 interaction

Monitor/Modify Tx

iopamidol + sodium tetradecyl sulfate

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• sotatercept
Isovue (iopamidol)

+

sotatercept

1 interaction

Monitor/Modify Tx

iopamidol + sotatercept

if IV iopamidol use, monitor Hgb, thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• sparsentan
Isovue (iopamidol)

+

sparsentan

1 interaction

Monitor/Modify Tx

iopamidol + sparsentan

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• spironolactone
Isovue (iopamidol)

+

spironolactone

1 interaction

Monitor/Modify Tx

iopamidol + spironolactone

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• sufentanil
Isovue (iopamidol)

+

sufentanil

1 interaction

Monitor/Modify Tx

iopamidol + sufentanil

caution advised if intrathecal iopamidol use; consider holding sufentanil at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• sulfate bowel prep
Isovue (iopamidol)

+

sulfate bowel prep

1 interaction

Monitor/Modify Tx

iopamidol + sulfate bowel prep

if IV iopamidol use, monitor renal fxn; caution advised if intrathecal iopamidol use; consider holding sulfate bowel prep at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of nephrotoxicity, seizures (additive effects)

• sulindac
Isovue (iopamidol)

+

sulindac

1 interaction

Monitor/Modify Tx

iopamidol + sulindac

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective sulindac dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• sumatriptan
Isovue (iopamidol)

+

sumatriptan

1 interaction

Monitor/Modify Tx

iopamidol + sumatriptan

caution advised if intrathecal iopamidol use; consider holding sumatriptan at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• sunitinib
Isovue (iopamidol)

+

sunitinib

1 interaction

Monitor/Modify Tx

iopamidol + sunitinib

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• tacrolimus
Isovue (iopamidol)

+

tacrolimus

1 interaction

Monitor/Modify Tx

iopamidol + tacrolimus

if IV iopamidol use, monitor renal fxn; caution advised if intrathecal iopamidol use; consider holding tacrolimus at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of nephrotoxicity, seizures (additive effects)

• tamoxifen
Isovue (iopamidol)

+

tamoxifen

1 interaction

Monitor/Modify Tx

iopamidol + tamoxifen

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• tapentadol
Isovue (iopamidol)

+

tapentadol

1 interaction

Monitor/Modify Tx

iopamidol + tapentadol

caution advised if intrathecal iopamidol use; consider holding tapentadol at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• teclistamab
Isovue (iopamidol)

+

teclistamab

1 interaction

Monitor/Modify Tx

iopamidol + teclistamab

caution advised if intrathecal iopamidol use; consider holding teclistamab at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• telavancin
Isovue (iopamidol)

+

telavancin

1 interaction

Monitor/Modify Tx

iopamidol + telavancin

if IV iopamidol use, monitor ECG, renal fxn: combo may incr. telavancin levels, risk of QT prolongation, cardiac arrhythmias, nephrotoxicity, other adverse effects (additive effects)

• telmisartan
Isovue (iopamidol)

+

telmisartan

1 interaction

Monitor/Modify Tx

iopamidol + telmisartan

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• temsirolimus
Isovue (iopamidol)

+

temsirolimus

1 interaction

Monitor/Modify Tx

iopamidol + temsirolimus

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• tenofovir alafenamide
Isovue (iopamidol)

+

tenofovir alafenamide

1 interaction

Monitor/Modify Tx

iopamidol + tenofovir alafenamide

if IV iopamidol use, monitor renal fxn: combo may incr. tenofovir levels, risk of nephrotoxicity, other adverse effects (additive effects)

• terbutaline
Isovue (iopamidol)

+

terbutaline

1 interaction

Monitor/Modify Tx

iopamidol + terbutaline

caution advised if intrathecal iopamidol use; consider holding terbutaline at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• testosterone
Isovue (iopamidol)

+

testosterone

1 interaction

Monitor/Modify Tx

iopamidol + testosterone

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• thalidomide
Isovue (iopamidol)

+

thalidomide

1 interaction

Monitor/Modify Tx

iopamidol + thalidomide

if IV iopamidol use, monitor thrombosis s/sx; caution advised if intrathecal iopamidol use; consider holding thalidomide at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of thromboembolism, seizures (additive effects)

• theophylline
Isovue (iopamidol)

+

theophylline

1 interaction

Monitor/Modify Tx

iopamidol + theophylline

caution advised if intrathecal iopamidol use; consider holding theophylline at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• thioridazine
Isovue (iopamidol)

+

thioridazine

1 interaction

Monitor/Modify Tx

iopamidol + thioridazine

caution advised if intrathecal iopamidol use; consider holding thioridazine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• thiotepa
Isovue (iopamidol)

+

thiotepa

1 interaction

Monitor/Modify Tx

iopamidol + thiotepa

caution advised if intrathecal iopamidol use; consider holding thiotepa at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• thiothixene
Isovue (iopamidol)

+

thiothixene

1 interaction

Monitor/Modify Tx

iopamidol + thiothixene

caution advised if intrathecal iopamidol use; consider holding thiothixene at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• tinidazole
Isovue (iopamidol)

+

tinidazole

1 interaction

Monitor/Modify Tx

iopamidol + tinidazole

caution advised if intrathecal iopamidol use; consider holding tinidazole at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• tiopronin
Isovue (iopamidol)

+

tiopronin

1 interaction

Monitor/Modify Tx

iopamidol + tiopronin

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• tisagenlecleucel
Isovue (iopamidol)

+

tisagenlecleucel

1 interaction

Monitor/Modify Tx

iopamidol + tisagenlecleucel

caution advised if intrathecal iopamidol use: combo may incr. risk of seizures (additive effects)

• tivozanib
Isovue (iopamidol)

+

tivozanib

1 interaction

Monitor/Modify Tx

iopamidol + tivozanib

if IV iopamidol use, monitor renal fxn, thrombosis s/sx: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• tofacitinib
Isovue (iopamidol)

+

tofacitinib

1 interaction

Monitor/Modify Tx

iopamidol + tofacitinib

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• tolmetin
Isovue (iopamidol)

+

tolmetin

1 interaction

Monitor/Modify Tx

iopamidol + tolmetin

if IV iopamidol use, monitor renal fxn, thrombosis s/sx; use lowest effective tolmetin dose, shortest effective tx duration: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• toremifene
Isovue (iopamidol)

+

toremifene

1 interaction

Monitor/Modify Tx

iopamidol + toremifene

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• torsemide
Isovue (iopamidol)

+

torsemide

1 interaction

Monitor/Modify Tx

iopamidol + torsemide

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• tramadol
Isovue (iopamidol)

+

tramadol

1 interaction

Monitor/Modify Tx

iopamidol + tramadol

caution advised if intrathecal iopamidol use; consider holding tramadol at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• trametinib
Isovue (iopamidol)

+

trametinib

1 interaction

Monitor/Modify Tx

iopamidol + trametinib

if IV iopamidol use, monitor thrombosis s/sx, especially in combo w/ dabrafenib: combo may incr. risk of thromboembolism (additive effects)

• trandolapril
Isovue (iopamidol)

+

trandolapril

1 interaction

Monitor/Modify Tx

iopamidol + trandolapril

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• tranylcypromine
Isovue (iopamidol)

+

tranylcypromine

1 interaction

Monitor/Modify Tx

iopamidol + tranylcypromine

caution advised if intrathecal iopamidol use; consider holding tranylcypromine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• tretinoin
Isovue (iopamidol)

+

tretinoin

1 interaction

Monitor/Modify Tx

iopamidol + tretinoin

if IV iopamidol use, monitor thrombosis s/sx, especially during 1st month of tretinoin use: combo may incr. risk of thromboembolism (additive effects)

• triamcinolone
Isovue (iopamidol)

+

triamcinolone

1 interaction

Monitor/Modify Tx

iopamidol + triamcinolone

caution advised if intrathecal iopamidol use; consider holding triamcinolone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• triamterene
Isovue (iopamidol)

+

triamterene

1 interaction

Monitor/Modify Tx

iopamidol + triamterene

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• trifluoperazine
Isovue (iopamidol)

+

trifluoperazine

1 interaction

Monitor/Modify Tx

iopamidol + trifluoperazine

caution advised if intrathecal iopamidol use; consider holding trifluoperazine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• trimipramine
Isovue (iopamidol)

+

trimipramine

1 interaction

Monitor/Modify Tx

iopamidol + trimipramine

caution advised if intrathecal iopamidol use; consider holding trimipramine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• triptorelin
Isovue (iopamidol)

+

triptorelin

1 interaction

Monitor/Modify Tx

iopamidol + triptorelin

caution advised if intrathecal iopamidol use; consider holding triptorelin at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• upadacitinib
Isovue (iopamidol)

+

upadacitinib

1 interaction

Monitor/Modify Tx

iopamidol + upadacitinib

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• vadadustat
Isovue (iopamidol)

+

vadadustat

1 interaction

Monitor/Modify Tx

iopamidol + vadadustat

if IV iopamidol use, monitor Hgb, thrombosis s/sx; use lowest effective vadadustat dose; consider holding vadadustat at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of thromboembolism, seizures (additive effects)

• valacyclovir
Isovue (iopamidol)

+

valacyclovir

1 interaction

Monitor/Modify Tx

iopamidol + valacyclovir

if IV iopamidol use, monitor renal fxn; caution advised if intrathecal iopamidol use; consider holding valacyclovir at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. acyclovir levels, risk of nephrotoxicity, seizures, other adverse effects (additive effects)

• valoctocogene roxaparvovec
Isovue (iopamidol)

+

valoctocogene roxaparvovec

1 interaction

Monitor/Modify Tx

iopamidol + valoctocogene roxaparvovec

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• valsartan
Isovue (iopamidol)

+

valsartan

1 interaction

Monitor/Modify Tx

iopamidol + valsartan

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• vamorolone
Isovue (iopamidol)

+

vamorolone

1 interaction

Monitor/Modify Tx

iopamidol + vamorolone

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• vancomycin
Isovue (iopamidol)

+

vancomycin

1 interaction

Monitor/Modify Tx

iopamidol + vancomycin

VANCOMYCIN IV: monitor renal fxn, vancomycin levels, ototoxicity if IV iopamidol use; VANCOMYCIN PO: consider monitoring renal fxn, vancomycin levels, ototoxicity in pts w/ severe renal impairment, severe intestinal inflammation, or prolonged course >2 g/day if IV iopamidol use: combo may incr. vancomycin levels, risk of nephrotoxicity, auditory, vestibular, other adverse effects (additive effects; incr. oral vancomycin absorption if inflamed or compromised gut mucosa)

• varenicline
Isovue (iopamidol)

+

varenicline

1 interaction

Monitor/Modify Tx

iopamidol + varenicline

caution advised if intrathecal iopamidol use; consider holding varenicline at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• varicella zoster immune globulin
Isovue (iopamidol)

+

varicella zoster immune globulin

1 interaction

Monitor/Modify Tx

iopamidol + varicella zoster immune globulin

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• venlafaxine
Isovue (iopamidol)

+

venlafaxine

1 interaction

Monitor/Modify Tx

iopamidol + venlafaxine

caution advised if intrathecal iopamidol use; consider holding venlafaxine at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• vilazodone
Isovue (iopamidol)

+

vilazodone

1 interaction

Monitor/Modify Tx

iopamidol + vilazodone

caution advised if intrathecal iopamidol use; consider holding vilazodone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• voclosporin
Isovue (iopamidol)

+

voclosporin

1 interaction

Monitor/Modify Tx

iopamidol + voclosporin

if IV iopamidol use, monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

• von Willebrand factor
Isovue (iopamidol)

+

von Willebrand factor

1 interaction

Monitor/Modify Tx

iopamidol + von Willebrand factor

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• vorinostat
Isovue (iopamidol)

+

vorinostat

1 interaction

Monitor/Modify Tx

iopamidol + vorinostat

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

• willow bark
Isovue (iopamidol)

+

willow bark

1 interaction

Monitor/Modify Tx

iopamidol + willow bark

monitor renal fxn, especially w/ high-dose willow bark: combo may incr. risk of nephrotoxicity (additive effects, willow bark may contain salicylates)

• ziprasidone
Isovue (iopamidol)

+

ziprasidone

1 interaction

Monitor/Modify Tx

iopamidol + ziprasidone

caution advised if intrathecal iopamidol use; consider holding ziprasidone at least 48h before and at least 24h after intrathecal iopamidol: combo may incr. risk of seizures (additive effects)

• ziv-aflibercept
Isovue (iopamidol)

+

ziv-aflibercept

1 interaction

Monitor/Modify Tx

iopamidol + ziv-aflibercept

if IV iopamidol use, monitor renal fxn, thrombosis s/sx: combo may incr. risk of nephrotoxicity, thromboembolism (additive effects)

• zoledronic acid
Isovue (iopamidol)

+

zoledronic acid

1 interaction

Monitor/Modify Tx

iopamidol + zoledronic acid

if IV iopamidol use, monitor renal fxn: combo may incr. zoledronic acid levels, risk of nephrotoxicity, other adverse effects (additive effects)

• zonisamide
Isovue (iopamidol)

+

zonisamide

1 interaction

Monitor/Modify Tx

iopamidol + zonisamide

if IV iopamidol use, monitor renal fxn; caution advised if intrathecal iopamidol use: combo may incr. risk of nephrotoxicity; may alter seizure control (additive effects; antagonistic effects, intrathecal iopamidol may decr. seizure threshold)

• zopapogene imadenovec
Isovue (iopamidol)

+

zopapogene imadenovec

1 interaction

Monitor/Modify Tx

iopamidol + zopapogene imadenovec

if IV iopamidol use, monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)