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Benzedrex
propylhexedrine nasal
Dosing .
6 yo and older
- [ nasal inhaler ]
- Dose: 2 inhalations in each nostril q2h prn; Max: q2h for up to 3 days; Info: D/C if rebound congestion occurs
renal dosing
- [ not defined ]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [ not defined ]
Formulations .
nasal inhaler
- [active ingredients]
- 0.4-0.5 mg propylhexedrine per 800 mL inspired air (175 mg propylhexedrine per container)
Contraindications / Cautions .
- hypersensitivity to drug or ingredient
- oral use
- IV use
Drug Interactions .
Overview
propylhexedrine nasal
alpha-1 agonist nasal
- None
Avoid/Use Alternative
- zavegepant
Monitor/Modify Tx
- esketamine
- nafarelin nasal
Caution Advised
- butorphanol
Adverse Reactions .
Serious Reactions
- abuse potential
Common Reactions
- nasal burning
- nasal stinging
- sneezing
- rhinorrhea
- rebound congestion
Pregnancy/Lactation .
Pregnancy
Clinical Summary
may use during pregnancy; no human data available, though risk of fetal harm not expected based on expected limited systemic absorption
Lactation
Clinical Summary
may use while breastfeeding; no human data available, though risk of infant harm and adverse effects on milk production not expected based on limited systemic absorption in breastfeeding patients
Pharmacology .
Metabolism: for propylhexedrine: liver; CYP450: unknown; Info: minimal systemic absorption
Excretion: for propylhexedrine: urine; Half-life: unknown
Subclass: Decongestants, Intranasal
Mechanism of Action: for propylhexedrine: stimulates smooth muscle alpha adrenergic receptors, producing vasoconstriction and reducing nasal congestion (sympathomimetic)
Alternatives .
Search for Alternative Products by:
- Other OTCs w/ Same Active Ingredient(s)
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- Same Subclass
- Decongestants, Intranasal
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