Highlights & Basics
- IgA vasculitis (formerly known as Henoch-Schonlein purpura) is the most common vasculitis of childhood.
- Rash of palpable purpura is present in all cases.
- Most cases are self-limiting or resolve with symptomatic treatment.
- Long-term complications are rare but there is a risk of chronic kidney disease.
- Early, accurate diagnosis is important to initiate appropriate management.
Quick Reference
History & Exam
Key Factors
Other Factors
Diagnostics Tests
Treatment Options
Definition
Epidemiology
Etiology
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Citations
Ozen S, Pistorio A, Iusan SM, et al; Paediatric Rheumatology International Trials Organisation (PRINTO). EULAR/PRINTO/PRES criteria for Henoch-Schönlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: final classification criteria. Ann Rheum Dis. 2010 May;69(5):798-806.[Abstract][Full Text]
Mills JA, Michel BA, Bloch DA, et al. The American College of Rheumatology 1990 criteria for the classification of Henoch-Schonlein purpura. Arthritis Rheum. 1990 Aug;33(8):1114-21.[Abstract]
Ozen S, Marks SD, Brogan P, et al. European consensus-based recommendations for diagnosis and treatment of immunoglobulin A vasculitis - the SHARE initiative. Rheumatology (Oxford). 2019 Sep 1;58(9):1607-16.[Abstract][Full Text]
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