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Diseases

Ganglion cyst

OVERVIEW

  • Highlights & Basics
  • Images

DIAGNOSIS

  • Diagnostic Approach
  • Risk Factors
  • History & Exam
  • Tests
  • Differential Diagnosis
  • Criteria
  • Screening

TREATMENT

  • Tx Approach
  • Tx Options
  • Emerging Tx
  • Prevention

FOLLOW-UP

  • Overview
  • Complications

REFERENCES

  • Citations
  • Guidelines
  • Credits

PATIENT RESOURCES

  • Patient Instructions

Highlights & Basics

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Key Highlights
  • Ganglion cysts are the most common benign lesion of the hand/wrist.

  • Typically, insidious onset with no predisposing conditions.

  • Usually only a cosmetic problem but local pain and neurovascular compression may occur.

  • Conservative management usually suffices if no neurovascular compromise.

  • Aspiration of dorsal cysts can be therapeutic and diagnostic.

Typical dorsal wrist ganglion cyst
Typical dorsal wrist ganglion cyst
From the collection of Marco Rizzo, MD, Mayo Clinic; used with permission

Quick Reference

  • History & Exam

    • Key Factors

      • Other Factors

        More information...
      • Diagnostics Tests

          More information...
        • Treatment Options

            More information...

          Definition

          Epidemiology

          Etiology

          Pathophysiology

          content by BMJ Group
          Last updated

          Images

          • Typical dorsal wrist ganglion cyst

            Typical dorsal wrist ganglion cyst

          • ​Transillumination of ganglion cyst using pentorch

            ​Transillumination of ganglion cyst using pentorch

          Citations

            Key Articles

            • ​American College of Radiology. ACR appropriateness criteria: soft tissue masses. 2022 [internet publication].[Full Text]

            • American College of Radiology. ACR appropriateness criteria: chronic hand and wrist pain. 2023 [internet publication].[Full Text]

            • Lee I. Clinical treatments for wrist ganglia. ASERNIP-S Report No. 63. Adelaide, South Australia: ASERNIP-S, October 2008 [internet publication].[Full Text]

            Referenced Articles

            • 1. Athanasian E. Bone and soft tissue tumors. In: Green DP, Hotchkiss RN, Peterson WC, et al, eds. Green's operative hand surgery. 5th ed. Churchill Livingston; 2005:2221-32.

            • 2. Steen MW, Hofstede DJ. Ganglion and synovial cyst of the temporomandibular joint: a case report and literature review. Plast Reconstr Surg Glob Open. 2015 Sep;3(9):e524.[Abstract][Full Text]

            • 3. Coffey MJ, Fazlur Rahman M, Thirkannad SM. Pediatric ganglion cysts of the hand and wrist: an epidemiologic analysis. Hand (NY). 2008 Dec;3(4):359-62.[Abstract]

            • 4. Bram JT, Falk DP, Chang B, et al. Clinical presentation and characteristics of hand and wrist ganglion cysts in children. J Hand Surg Am. 2021 Apr 19:S0363-5023(21)00160-X.[Abstract][Full Text]

            • 5. Minotti P, Taras JS. Ganglion cysts of the wrist. Journal of American Society for Surgery of the Hand. 2002 May;2(2):102-7.

            • 6. Nelson CL, Sawmiller S, Phalen GS. Ganglions of the wrist and hand. J Bone Joint Surg Am. 1972 Oct;54(7):1459-64.

            • 7. Osterman AL, Raphael J. Arthroscopic resection of dorsal ganglion of the wrist. Hand Clin. 1995 Feb;11(1):7-12.[Abstract]

            • 8. Watson HK, Rogers WD, Ashmead D 4th. Reevaluation of the cause of the wrist ganglion. J Hand Surg Am. 1989 Sep;14(5):812-7.[Abstract]

            • 9. Andren L, Eiken O. Arthrographic studies of wrist ganglions. J Bone Joint Surg Am. 1971 Mar;53(2):299-302.

            • 10. Psaila JV, Mansel RE. The surface ultrastructure of ganglia. J Bone Joint Surg Br. 1978 May;60-B(2):228-33.[Abstract]

            • 11. Gude W, Morelli V. Ganglion cysts of the wrist: pathophysiology, clinical picture, and management. Curr Rev Musculoskelet Med. 2008 Aug 26;1(3-4):205-11.[Abstract]

            • 12. Soren A. Pathogenesis and treatment of ganglion. Clin Orthop Relat Res. 1966 Sep-Oct;48:173-9.

            • 13. Greendyke SD, Wilson M, Shepler TR. Anterior wrist ganglia from the scaphotrapezial joint. J Hand Surg Am. 1992 May;17(3):487-90.[Abstract]

            • 14. Ho PC, Griffiths J, Lo WN, et al. Current treatment of ganglion of the wrist. Hand Surg. 2001 Jul;6(1):49-58.[Abstract]

            • 15. Brooks DM. Nerve compression by simple ganglia: a review of thirteen collected cases. J Bone Joint Surg Br. 1952 Aug;34-B(3):391-400.

            • 16. Wong AS, Jebson PJ, Murray PM, et al. The use of routine wrist radiography is not useful in the evaluation of patients with a ganglion cyst of the wrist. Hand (NY). 2007 Sep;2(3):117-9.[Abstract][Full Text]

            • 17. ​American College of Radiology. ACR appropriateness criteria: soft tissue masses. 2022 [internet publication].[Full Text]

            • 18. American College of Radiology. ACR appropriateness criteria: chronic hand and wrist pain. 2023 [internet publication].[Full Text]

            • 19. Blam O, Bindra R, Middleton W, et al. The occult dorsal carpal ganglion: usefulness of magnetic resonance imaging and ultrasound in diagnosis. Am J Orthop. 1998 Feb;27(2):107-10.[Abstract]

            • 20. Zanetti M, Saupe N, Nagy L. Role of MR imaging in chronic wrist pain. Eur Radiol. 2007 Apr;17(4):927-38.[Abstract]

            • 21. Goldsmith S, Yang SS. Magnetic resonance imaging in the diagnosis of occult dorsal wrist ganglions. J Hand Surg Eur Vol. 2008 Oct;33(5):595-9.[Abstract]

            • 22. Plate AM, Lee SJ, Steiner G, et al. Tumorlike lesions and benign tumors of the hand and wrist. J Am Acad Orthop Surg. 2003 Mar-Apr;11(2):129-41.[Abstract][Full Text]

            • 23. Teefey SA, Dahiya N, Middleton WD, et al. Ganglia of the hand and wrist: a sonographic analysis. AJR Am J Roentgenol. 2008 Sep;191(3):716-20.[Abstract]

            • 24. Lee I. Clinical treatments for wrist ganglia. ASERNIP-S Report No. 63. Adelaide, South Australia: ASERNIP-S, October 2008 [internet publication].[Full Text]

            • 25. Suen M, Fung B, Lung CP. Treatment of ganglion cysts. ISRN Orthop. 2013;2013:940615.[Abstract][Full Text]

            • 26. Dias JJ, Dhukaram V, Kumar P. The natural history of untreated dorsal wrist ganglia and patient reported outcome 6 years after intervention. J Hand Surg Eur Vol. 2007 Oct;32(5):502-8.[Abstract]

            • 27. Calif E, Stahl S, Stahl S. Simple wrist ganglia in children: a follow-up study. J Pediatr Orthop B. 2005 Nov;14(6):448-50.[Abstract]

            • 28. Dias J, Buch K. Palmar wrist ganglion: does intervention improve outcome? A prospective study of the natural history and patient-reported treatment outcomes. J Hand Surg Br. 2003 Apr;28(2):172-6.[Abstract][Full Text]

            • 29. Richman JA, Gelberman RH, Engber WD, et al. Ganglions of the wrist and digits: results of treatment by aspiration and cyst wall puncture. J Hand Surg Am. 1987 Nov;12(6):1041-3.[Abstract]

            • 30. Zubowicz VN, Ishii CH. Management of ganglion cysts of the hand by simple aspiration. J Hand Surg Am. 1987 Jul;12(4):618-20.[Abstract]

            • 31. Varley GW, Needoff M, Davis TR, et al. Conservative management of wrist ganglia. Aspiration versus steroid infiltration. J Hand Surg Br. 1997 Oct;22(5):636-7.[Abstract]

            • 32. Urits I, Smoots D, Anantuni L, et al. Injection techniques for common chronic pain conditions of the hand: a comprehensive review. Pain Ther. 2020 Jun;9(1):129-42.[Abstract][Full Text]

            • 33. Head L, Gencarelli JR, Allen M, et al. Wrist ganglion treatment: systematic review and meta-analysis. J Hand Surg Am. 2015 Mar;40(3):546-53.e8.[Abstract][Full Text]

            • 34. Mooney ML, Jacobs CA, Prusick VW, et al. Pediatric ganglion cyst recurrence: location isn't the only risk factor. J Pediatr Orthop. 2020 Aug;40(7):340-3.[Abstract]

            • 35. Crawford C, Keswani A, Lovy AJ, et al. Arthroscopic versus open excision of dorsal ganglion cysts: a systematic review. J Hand Surg Eur Vol. 2018 Jul;43(6):659-64.[Abstract][Full Text]

            • 36. Kang L, Akelman E, Weiss AP. Arthroscopic versus open dorsal ganglion excision: a prospective, randomized comparison of rates of recurrence and of residual pain. J Hand Surg Am. 2008 Apr;33(4):471-5.[Abstract]

            • 37. Clay NR, Clement DA. The treatment of dorsal wrist ganglia by radical excision. J Hand Surg Br. 1988 May;13(2):187-91.[Abstract]

            • 38. Wright TW, Cooney WP, Ilstrup DM. Anterior wrist ganglion. J Hand Surg Am. 1994 Nov;19(6):954-8.[Abstract]

            • 39. Luchetti R, Badia A, Alfarano M, et al. Arthroscopic resection of dorsal wrist ganglia and treatment of recurrences. J Hand Surg Br. 2000 Feb;25(1):38-40.[Abstract]

            • 40. Bontempo NA, Weiss AP. Arthroscopic excision of ganglion cysts. Hand Clin. 2014 Feb;30(1):71-5.[Abstract][Full Text]

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