Kerendia

Adult Dosing .

Dosage forms:  TAB: 10 mg, 20 mg, 40 mg

kidney dz progression and cardiovascular-associated risk reduction - DM type 2 patients w/ CKD

[20 mg PO qd]

Info: see pkg insert for dose adjustments based on potassium levels

heart failure-associated risk reduction - heart failure patients w/ LVEF >40%

[40 mg PO qd]

Start: 20 mg PO qd, may incr. to 40 mg PO qd after 4wk based on potassium level and eGFR; Info: see pkg insert for dose adjustments based on potassium levels and eGFR

renal dosing

[see below]

eGFR 25-59: start 10 mg qd, may incr. to 20 mg qd after 4wk based on potassium level and eGFR; eGFR <25: avoid tx initiation; Info: see pkg insert for dose adjustments based on potassium levels and eGFR

HD/PD: not defined

hepatic dosing

[see below]

Child-Pugh Class C: avoid use

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.