Saphnelo (anifrolumab-fnia)

Adult Dosing .

Dosage forms:  INJ (SC auto-injector): 120 mg; INJ (SC pre-filled syringe): 120 mg per 0.8 mL; INJ (IV vial): various

Special Note

[drug name clarification]

Info: nonproprietary name = anifrolumab-fnia

moderate-severe SLE, adjunct tx

[300 mg IV q4wk]

Alt: 120 mg SC qwk; Info: may switch from IV to SC route approximately 2wk after last IV administration; may switch from SC to IV route approximately 3-4wk after last SC administration

renal dosing

[see below]

eGFR >30: no adjustment; eGFR <30 or ESRD: not defined

HD/PD: not defined

hepatic dosing

[no adjustment]

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.