Scemblix

Adult Dosing .

Dosage forms:  TAB: 20 mg, 40 mg

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

Ph-positive CML, chronic phase

[T315I-negative dz]

Dose: 80 mg PO daily; Alt: 40 mg PO bid; Info: avoid food for at least 2h before and 1h after admin; do not cut/crush/chew tab

[T315I-positive dz]

Dose: 200 mg PO bid; Info: avoid food for at least 2h before and 1h after admin; do not cut/crush/chew tab

renal dosing

[see below]

eGFR >15: no adjustment; eGFR <15: not defined

HD/PD: not defined

hepatic dosing

[no adjustment]

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.