Leqvio

Adult Dosing .

Dosage forms:  INJ (pre-filled syringe): 284 mg per 1.5 mL

hypercholesterolemia

[284 mg SC q6mo]

Start: 284 mg SC q3mo x2, then 284 mg SC q6mo; Info: restart dosing schedule if missed dose >3mo

heterozygous familial hypercholesterolemia

[284 mg SC q6mo]

Start: 284 mg SC q3mo x2, then 284 mg SC q6mo; Info: restart dosing schedule if missed dose >3mo

renal dosing

[see below]

renal impairment: no adjustment; ESRD: not defined

HD/PD: not defined

hepatic dosing

[see below]

mild-moderate impairment: no adjustment; severe impairment: not defined

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.