Vivjoa

Adult Dosing .

Dosage forms:  CAP: 150 mg

vulvovaginal candidiasis, recurrence reduction

[induction phase]

Dose: 600 mg PO x1 on day 1, then 450 mg PO x1 on day 2; Info: for female pts w/ permanent infertility; do not open/dissolve cap; give w/ food

[maintenance phase]

Dose: 150 mg PO qwk x11wk; Start: 2wk after starting induction phase regimen; Info: for female pts w/ permanent infertility; do not open/dissolve cap; give w/ food

[maintenance phase following fluconazole induction]

Dose: 150 mg PO qd x7 days, then 150 mg PO qwk x11wk; Start: 7 days after completing fluconazole 150 mg PO q72h x3 doses; Info: for female pts w/ permanent infertility; do not open/dissolve cap; give w/ food

renal dosing

[see below]

eGFR >15: no adjustment; eGFR <15: not defined

HD/PD: not defined

hepatic dosing

[see below]

Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined

Peds Dosing .

Dosage forms:  CAP: 150 mg

vulvovaginal candidiasis, recurrence reduction

[induction phase, postmenarchal female pts]

Dose: 600 mg PO x1 on day 1, then 450 mg PO x1 on day 2; Info: for pts w/ permanent infertility; do not open/dissolve cap; give w/ food

[maintenance phase, postmenarchal female pts]

Dose: 150 mg PO qwk x11wk; Start: 2wk after starting induction phase regimen; Info: for pts w/ permanent infertility; do not open/dissolve cap; give w/ food

[maintenance phase following fluconazole induction, postmenarchal female pts]

Dose: 150 mg PO qd x7 days, then 150 mg PO qwk x11wk; Start: 7 days after completing fluconazole 150 mg PO q72h x3 doses; Info: for pts w/ permanent infertility; do not open/dissolve cap; give w/ food

renal dosing

[see below]

eGFR >15: no adjustment; eGFR <15: not defined

HD/PD: not defined

hepatic dosing

[see below]

Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined