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Jaypirca
pirtobrutinib
Adult Dosing .
Dosage forms: TAB: 50 mg, 100 mg
Special Note
- [uses, dosing may vary]
- Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments; consider holding tx x3-7 days before and after surgery if bleeding risk
mantle cell lymphoma, relapsed or refractory
- [200 mg PO qd]
- Info: for pts who have received at least 2 prior tx, incl a BTK inhibitor; do not cut/crush/chew tab
CLL/SLL, relapsed or refractory
- [200 mg PO qd]
- Info: for pts who have received at least 2 prior tx, incl a BTK inhibitor and a BCL-2 inhibitor; do not cut/crush/chew tab
renal dosing
- [if usual dose 200 mg qd]
- eGFR 15-29: 100 mg qd; eGFR <15: not defined
- HD/PD: not defined
- [if usual dose <200 mg qd]
- eGFR 15-29: decr. dose by 50 mg; eGFR <15: not defined
- HD/PD: not defined
hepatic dosing
- [no adjustment]
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.