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Lamzede (velmanase alfa-tycv)
velmanase alfa
Black Box Warnings .
Severe Hypersensitivity Reaction
severe reactions including anaphylaxis have occurred; appropriate medical support including cardiopulmonary resuscitation equipment should be readily available during administration; D/C immediately and start appropriate tx if severe reaction occurs; may consider desensitization procedure in patients with severe reaction
Adult Dosing .
Dosage forms: INJ
Special Note
- [drug name clarification]
- Info: nonproprietary name = velmanase alfa-tycv
alpha-mannosidosis
- [1 mg/kg/dose IV qwk]
- Info: for patients with non-CNS manifestations; consider premed with antihistamine, antipyretic, and/or corticosteroid; see pkg insert for dose adjustments based on hypersensitivity and infusion reactions
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: INJ
Special Note
- [drug name clarification]
- Info: nonproprietary name = velmanase alfa-tycv
alpha-mannosidosis
- [1 mg/kg/dose IV qwk]
- Info: for patients with non-CNS manifestations; consider premed with antihistamine, antipyretic, and/or corticosteroid; see pkg insert for dose adjustments based on hypersensitivity and infusion reactions
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]