Loqtorzi (toripalimab-tpzi)

Adult Dosing .

Dosage forms:  INJ

Special Note

[drug name clarification]

Info: nonproprietary name = toripalimab-tpzi

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

nasopharyngeal CA

[first-line tx, combo tx]

Dose: 240 mg IV q3wk for up to 24mo; Info: for pts w/ metastatic or recurrent locally advanced dz

[previously treated dz, monotherapy]

Dose: 3 mg/kg/dose IV q2wk; Info: for pts w/ metastatic or recurrent unresectable dz w/ progression on or after platinum-containing chemo

renal dosing

[see below]

CrCl >60: no adjustment; CrCl <60: not defined

HD/PD: not defined

hepatic dosing

[see below]

bilirubin 1.1-1.5x ULN or AST >ULN: no adjustment; bilirubin >1.5x ULN: not defined

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.