Cobenfy

Adult Dosing .

Dosage forms:  CAP: 50 mg/20 mg, 100 mg/20 mg, 125 mg/30 mg; convenience pack

Special Note

[convenience pack components]

Info: 4-wk starter pack contains 50 mg/20 mg cap x4 and 100 mg/20 mg cap x52

schizophrenia

[100 mg/20 mg-125 mg/30 mg PO bid]

Start: 50 mg/20 mg PO bid for at least 2 days, then incr. to 100 mg/20 mg PO bid for at least 5 days, then may incr. to 125 mg/30 mg PO bid; Max: 250 mg/60 mg/day; Info: give >1h before or >2h after meal; do not open cap; max 200 mg/40 mg/day in elderly pts

renal dosing

[see below]

eGFR <60: avoid use

HD/PD: not defined

hepatic impairment

[see below]

Child-Pugh Class A: avoid use; Child-Pugh Class B or C: contraindicated

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.