Lazcluze

Adult Dosing .

Dosage forms:  TAB: 80 mg, 240 mg

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses, concomitant meds, and dosing incl. toxicity-related dose adjustments

non-small cell lung CA, locally advanced or metastatic

[240 mg PO qd]

Info: for pts w/ EGFR exon 19 deletions or exon 21 (L858R) substitution mutations; use w/ amivantamab; give anticoagulant prophylaxis x4mo; do not cut/crush/chew tab

renal dosing

[see below]

eGFR >30: no adjustment; eGFR <30: not defined

HD/PD: not defined

hepatic dosing

[see below]

bilirubin <3x ULN: no adjustment; bilirubin >3x ULN: not defined

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.