hydroxocobalamin IM injection

Adult Dosing .

Dosage forms:  INJ

vitamin B12 deficiency

[w/o neurological involvement]

Dose: 1000 mcg IM q2-3mo; Start: 1000 mcg IM 3x/wk x2wk; Alt: 30 mcg IM qd x5-10 days, then 100-200 mcg IM qmo

[w/ neurological involvement]

Dose: 1000 mcg IM q2mo; Start: 1000 mcg IM qod until no further improvement; Info: consider reassessing need for qod tx after 3wk

pernicious anemia

[w/o neurological involvement]

Dose: 1000 mcg IM q2-3mo; Start: 1000 mcg IM 3x/wk x2wk; Alt: 30 mcg IM qd x5-10 days, then 100-200 mcg IM qmo

[w/ neurological involvement]

Dose: 1000 mcg IM q2mo; Start: 1000 mcg IM qod until no further improvement; Info: consider reassessing need for qod tx after 3wk

Schilling test flushing dose

[1000 mcg IM x1]

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ

vitamin B12 deficiency

[w/o neurological involvement]

Dose: 1000 mcg IM q2-3mo; Start: 1000 mcg IM 3x/wk x2wk; Alt: 1000-5000 mcg IM in 100 mcg increments over at least 2wk, then 30-50 mcg IM qmo

[w/ neurological involvement]

Dose: 1000 mcg IM q2mo; Start: 1000 mcg IM qod until no further improvement; Info: consider reassessing need for qod tx after 3wk

pernicious anemia

[w/o neurological involvement]

Dose: 1000 mcg IM q2-3mo; Start: 1000 mcg IM 3x/wk x2wk; Alt: 1000-5000 mcg IM in 100 mcg increments over at least 2wk, then 30-50 mcg IM qmo

[w/ neurological involvement]

Dose: 1000 mcg IM q2mo; Start: 1000 mcg IM qod until no further improvement; Info: consider reassessing need for qod tx after 3wk

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]